ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimm...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Acupressure reduced fatigue in breast cancer survivors

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Omega-3 fatty acid stops known trigger of lupus

Print Page
Email Article

Research into the Genetic Foundation of Osteoarthritis

  [ 15 votes ]   [ Discuss This Article ]
By News Release • • December 30, 1999

It's not difficult to find a family in which generations have struggled with the same inherited disease. One such disease, osteoarthritis, appears to be passed on from one generation to the next. Now a new international multi-center study is underway to identify the genes responsible for osteoarthritis. Understanding this genetic link may help researchers find more effective treatments for the disease.

The University of Maryland Medical Center is part of an international research network that has launched the largest study ever to find the genetic susceptibility for osteoarthritis, which affects more than 21 million Americans. The research network is comprised of seven university medical institutions in the United States and England, which are working together with the Center for Human Genetics at Duke University and Glaxo Wellcome, a pharamaceutical research company.

“Osteoarthritis is a highly debilitating and painful condition suffered by millions of people,” says Marc C. Hochberg, M.D., M.P.H., head of the Division of Rheumatology and Clinical Immunology at the University of Maryland Medical Center and principal investigator of the study. “We know that it is hereditary but we do not know which gene or genes carries the hereditary code. Finding a genetic basis for the disease will open up whole new possibilities for finding effective treatments and even preventive measures for this condition.”

The three-year study will enroll 1,400 families who have two or more siblings with primary generalized osteoarthritis, a form of arthritis that affects the hands, hips, knees and spine. Study participants will visit the research center only once to provide in-depth interviews about their general health, family history and risk factors for arthritis. In addition they will have a physical examination and provide a blood sample as well as x-rays of the hand, hip, knee and lower spine. The researchers will then analyze the DNA samples and x-rays and chart the family tree to try to identify the genes involved.

“We believe that by analyzing the DNA and health histories of a large group of patients with osteoarthritis, we can uncover an accurate understanding of the role single or multiple genes play in the development of the disease,” says Dr. Hochberg who is also professor of medicine at the University of Maryland School of Medicine. “This study will provide additional insight about osteoarthritis which will ultimately benefit patients.”

In osteoarthritis, the cartilage that covers the ends of the bones deteriorates, causing pain and loss of muscle function. While age is a major risk factor for developing osteoarthritis, the disease is not just an inevitable consequence of aging. Other risk factors include major joint trauma, repetitive stress, and obesity.

The pain of osteoarthritis is often described as a deep ache, specific to the affected joint. The pain is aggravated when the joint is used and subsides when the joint is at rest.However, as the disease progresses the pain can persist even when the joint is not being used. Inflammation and swelling at the joint may occur and cause physical deformity in the later stage. There is no current cure for osteoarthitis. Various treatment options can help alleviate the symptoms. Pain-killers and anti-inflammatory agents are the mainstay of drug therapy. However, therapy and lifestyle changes can also reduce the symptoms of the disease. Surgery, including joint replacement, is used when all else has failed.

Source: The University of Maryland Medicine

Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra EPA  - Fish Oil Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map