ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

16 Tips from 16 Years Sick

Fibromyalgia Fare Fit for All Seasons

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Higher vitamin D levels associated with less severe disease in NAFLD patients

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

How zinc helps fight esophageal cancer

Everything You Need to Know About Black Cohosh

Low vitamin D levels predict ED in diabetics

The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage

 
Print Page
Email Article

New Brain Cancer Treatment Extends Survival for More Patients

  [ 78 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 22, 2003


Patients stay home, take a pill instead of IV chemotherapy

A doctor at the James P. Wilmot Cancer Center has developed a new brain cancer treatment that, in a pilot study, shows promise at keeping more patients alive longer than the best current standard treatments for the disease. Preliminary findings were presented recently at the American Society of Clinical Oncology annual meeting in Chicago, and now the study is continuing for adults and will be expanded to include children nationwide.

The treatment is a combination of two cancer-killing drugs that can be taken orally as pills, making it easier on those patients who have already undergone difficult surgery, radiation or traditional, intravenous chemotherapy.

"It's not a miracle, but it's a piece of the struggle against brain cancer," says David N. Korones, M.D., principal investigator and associate professor of Pediatrics, Oncology, and Neurology at the University of Rochester Medical Center. "It's a new, somewhat innovative approach that has merit and offers better tolerance than traditional chemotherapy. It makes life much easier for these patients. Patients can stay home and simply take a pill, instead of coming into the hospital for several hours to be tethered to an IV."

Korones is the first to investigate the effectiveness of temozolomide and etoposide, given together for patients with recurrent malignant glioma, the most common brain tumor in adults. Each of the drugs, which have been approved by the Food and Drug Administration, has been used separately with some success. But Korones noticed that laboratory data showed synergies between the two medications, and he theorized they may work better in tandem.

Among the 24 adult patients he has followed so far, 16 percent saw their tumors shrink and 35 percent were stable with no disease progression after six months, compared to 10-20 percent of patients who stabilize after traditional chemotherapy. The results are encouraging, he says; the median survival time for brain cancer that recurs is just six months.

The medications have been reasonably well tolerated. With no need to come into the hospital for IV therapy, patients can stay home and report weekly for blood tests. In a pilot study of four children aged 10 or older, using doses comparable to the adults, Korones also noted that side effects were minimal, and the tumors shrunk dramatically.

Brain cancer consists of a mass of cells that do not belong there. But for cancer-fighting drugs to reach the mass, first they must be able to pass through the blood-brain barrier, which is cleverly designed to keep out toxins. Temozolomide and etoposide are effective at passing through the barrier, Korones says.
Schering-Plough Inc., manufacturer of temozolomide, is funding the research. With Korones as the principal investigator, other institutions participating are: Rochester General Hospital's Lipson Cancer and Blood Center; Roswell Park Cancer Institute, Buffalo; Dent Neurologic Institute, Buffalo; SUNY Health Science Center, Syracuse; The Brain Tumor Center at Duke University Medical Center, Durham, N.C.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra EPA  - Fish Oil Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More
The Super Antioxidant for Brain, Joint and Heart Health The Super Antioxidant for Brain, Joint and Heart Health
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map