ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Fighting Heartburn and Gerd Naturally – And Safely!

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Natural Bladder Control, Go Less and Live More

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Trimming the spare tire: Canola oil may cut belly fat

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

Curcumin Reverses the Cellular Damage of Chronic Stress

The Onion: Cancer Fighter and Food Preserver

Probiotics improve cognition in Alzheimer's patients

 
Print Page
Email Article

The 1 mug short Synacthen test in Chronic Fatigue Syndrome

  [ 16 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 10, 1999


OBJECTIVE: Many studies suggest mild hypocortisolism in
chronic fatigue syndrome (CFS), usually assumed to be due to
reduced suprahypothalamic drive to the
hypothalamo-pituitary-adrenal (HPA) axis. We wished to explore
further the state of the HPA axis in CFS using the 1 mug low
dose short Synacthen test.

DESIGN: Subjects received an
intravenous bolus of 1 mug Synacthen; samples for cortisol
estimation were taken at baseline and 2, 10, 20, 30, 40 and 60
minutes after injection.

PATIENTS: We tested 20 subjects
suffering from CFS according to the criteria of the Center for
Diseases Control without psychiatric comorbidity and 20
matched healthy controls. All subjects were drug free for at
least 1 month.

MEASUREMENTS: We calculated the cortisol
responses to the test as the maximum cortisol attained, the
incremental rise in cortisol over baseline (Deltavalue) and as
the integrated area under the curve.

RESULTS: There were no
significant differences in baseline cortisol or cortisol
responses between patients and controls. However, responses
generally were low, and many subjects' peak responses were
prior to the standard 30 minute sampling time.,

CONCLUSIONS
These results do not lend support to the theory that patients
with chronic fatigue syndrome have a low adrenal reserve.
However, results from studies assessing the HPA axis are
proving to be inconsistent. We suggest that many other factors
may be contributing to HPA axis alterations in chronic fatigue
syndrome, including sleep disturbance, inactivity, altered
circadian rhythmicity, illness chronicity, concomitant
medication and comorbid psychiatric disturbance. These sources
of heterogeneity need to be considered in future studies, and
may explain the inconsistent findings to date.

Hudson M, Cleare AJ




Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Energy NADH™ 12.5mg Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Vital Molecule Increases Cellular Energy and Improves Cognitive Function Vital Molecule Increases Cellular Energy and Improves Cognitive Function
The New Dual Activation Pain Relief Cream The New Dual Activation Pain Relief Cream
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Top 3 Nutrients to Detox the Liver and Soothe Digestion Top 3 Nutrients to Detox the Liver and Soothe Digestion

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map