ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Cognitive Impairment II

Top 3 Nutrients to Detox the Liver and Soothe Digestion

Natural Bladder Control, Go Less and Live More

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Omega Fix for Obesity: How the Right Fats Fight Fat

How Pomegranate May Protect Against Cancer

Trimming the spare tire: Canola oil may cut belly fat

The Onion: Cancer Fighter and Food Preserver

Safely Reduce a Common Cause of Stomach Distress

 
Print Page
Email Article

HIV Vaccine to be Tested in Botswana, US

  [ 43 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 27, 2003


By Jenny Badner

The southern African nation of Botswana has one of the highest rates of AIDS in the world. Health officials there are working with the School of Public Health at Harvard University to test a vaccine against HIV, the virus that causes AIDS. It is the first time a vaccine is being tested at the early stages simultaneously in Africa and the United States.

The AIDS epidemic in Africa has a significant biological difference from that in the United States and Europe. Africa has a different HIV strain.

The head of the Botswana-Harvard partnership, Max Essex, says this variation has led researchers to begin testing a vaccine on both continents, in a study funded by the U.S. National Institute of Health.

"For some time, we have been interested in having vaccines made that would incorporate some of the antigens for viruses that are more prevalent in Africa than in the United States," said Mr. Essex. "And also, I think, a lot of groups [around the world], including U.S. NIH, [are] interested in testing vaccines in Africa, especially southern Africa, because this is the area with highest prevalence in the world. So, you can get results faster, so to speak."

The vaccine trial is at its earliest stage. In June, 42 adults, equally divided between Botswana and the U.S. cities of Boston, and Saint Louis, received low doses of the vaccine, known as EP, HIV-10-90, to determine its safety. As a control, some of the participants are being given a placebo.

Researchers say it is not possible to contract HIV from the vaccine. California-based pharmaceutical company Epimmune developed the drug from synthetically produced HIV genes. The intent is for the vaccine to prompt the body to produce a protein, so the immune system can recognize and fight HIV infection.

This is not the first vaccine trial. The California drug company VaxGen earlier this year concluded that a three-year vaccine trial in industrialized countries did not show a statistically significant reduction in HIV infection. But the company has other vaccine trials in the works in Asia and Africa.

Botswana's ambassador to the United States, Caesar Lekoa, says it was easy to find volunteers for the study in his country, where people are desperate for a cure.

"Botswana, like many other countries, remains in a situation where the population is being decimated by the pandemic," explained Ambassador Lekoa. "We have seen a reduction in life expectancy from 70 years to around 45 years. And we are losing labor productivity as a result of people dying from HIV-AIDS, and so forth. So, a cure really will make all the difference for Botswana. For Botswana, this is really a catastrophe that really came from nowhere and visited our country."

Mr. Lekoa says he is encouraged by President Bush's pledge of $15 billion to fight HIV/AIDS in Africa and the Caribbean over the next five years, a commitment the president underscored during a recent trip to Botswana and other African countries.

Botswana is one of the most economically successful nations in sub-Saharan Africa. It was one of the first to offer a government drug-treatment program for AIDS.

But Ambassador Lekoa says Botswana needs guidance and resources from developed nations.

"We need first and foremost human capital, the manpower to implement the national response to the HIV/AIDS scourge," he said. "Secondly, we need to expand our medical facilities and related resources to deal with the heavier burden, or the additional burden that HIV has brought on to the capacity of existing facilities."

The independent Bill and Melinda Gates Foundation has dedicated $50 million to Botswana to fight AIDS. The country is also working closely with Harvard University on AIDS and HIV drug programs, and to prevent mother-to-infant infection.

Harvard School of Public Health Professor Max Essex says education and behavioral change are needed. But he says even a vaccine with a relatively low level of success would help reduce the deadly disease that has infected an estimated 42 million people around the world. "It would have tremendous impact in the long run, if we get a vaccine that has even 50 percent protection, which is, in the eyes of most vaccinologists who are more familiar with traditional vaccines, mumps, measles, rubella, polio, hepatitis etc., is a horrible vaccine," said Professor Essex. "But even one that only worked at that level in Botswana, in South Africa, in all of that region, would have tremendous value by reducing the number of new infections."

Researchers will study the vaccine's safety in Botswana and the United States for 18 months. Then, if it is not harmful, thousands of volunteers will test the vaccine's protective response. It could take at least five years to test and many more to produce and market a working vaccine against HIV/AIDS, which takes the lives of about 8,500 people a day worldwide.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Fighting Fatigue with Ground-breaking French Oak Wood Extract Fighting Fatigue with Ground-breaking French Oak Wood Extract
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map