ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Safflower: An Economically Important Herb That Can Benefit Humans and Animals Alike

Bacopa: The Herb That May Increase Your Brain Power

Lilac Oil: More Than Just for Fragrance

Eat More Yogurt and Avoid Osteoporosis

What Is Bilberry Good For?

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Higher omega 3 levels linked to improved brain blood flow

Curcumin, resveratrol, ursolic acid show promise against prostate cancer

 
Print Page
Email Article

Naturally Occurring Protein Could Slow Alzheimer's Disease

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 13, 2001


A laboratory "fishing expedition" landed a surprising catch for researchers: a cholesterol-lowering protein produced by the body that might be able to slow the progression of Alzheimer's disease. The findings are reported in March 27 issue of Biochemistry, a peer-reviewed journal of the American Chemical Society, the world's largest scientific society.

Using a protein implicated in Alzheimer's disease - amyloid precursor protein - for bait, University of Pittsburgh researchers trolled a "lake" of chemicals specifically designed to simulate the human body to see what might grab their unusual lure.

Effects of Amyloid Proteins

A small part of amyloid precursor protein forms a chemical called beta amyloid, which becomes the most important part of the Alzheimer's disease plaques that strangle normal brain cells.

The bait eventually produced a bite, another protein called Apolipoprotein A-1. Everyone has some quantity of Apolipoprotein A-1, or Apo-A, in their body, says Dr. Radosveta Koldamova, M.D., Ph.D., a member of the research team. It is produced in the small intestine and the liver and is known to help prevent coronary heart disease. At normal levels, the protein clears cholesterol throughout the body, including in the brain.

Boosting Apo-A Could Be Key

The scientists speculate that boosting Apo-A levels may also help clear beta amyloid.The researchers think that increasing the concentrations of Apo-A in blood might delay the dementia associated with Alzheimer's disease. Further testing is needed to confirm their hypothesis, they add. Another such protein, Apolipoprotein E, has been similarly linked with Alzheimer's and is being studied by other researchers.

"You begin to think about whether or not changing Apo-A levels in the blood could benefit Alzheimer's patients," Koldamova said.

How to Raise Apo-A Levels Naturally

One way to raise the levels of the protein naturally is through a good diet, according to Professor John S. Lazo, Ph.D., who led the research study. Previous findings indicate that some foods, including fruits, soybeans, coconut oil as well as some wines and teas can stimulate cells to make more Apo-A. Liver diseases or other infections can lower Apo-A levels, he said.

In previous clinical studies, Alzheimer's patients were shown to have lower than normal levels of Apo-A, leading Koldamova to suggest a direct relationship between the two.

"We think that if we can increase the concentration of Apo-A in the blood, we might be able to increase the levels of the protein in the brain," Koldamova said. "Our hypothesis is that this might help clear beta amyloid from the brain."

More Testing Needed

Further testing is needed to confirm the role of Apo-A in animals and its relation with Alzheimer's, she said. Then, new methods to boost the protein's concentrations in the blood would be needed before any human trials could begin, she continued.

Alzheimer’s Facts

Alzheimer's disease is a progressive, degenerative disease that causes a loss of brain function, primarily among elderly people. Approximately 4 million Americans currently have Alzheimer's disease and it is estimated that 14 million Americans will have the disease by the middle of the century unless a cure or prevention is found, according to the National Institute of Aging. There is no known cure for Alzheimer's disease.

This study was funded by the U.S. Public Health Service, a division of the U.S. Department of Health and Human Services, and the Fiske Drug Discovery Fund at the University of Pittsburgh.



Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra ATP+, Double Strength Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Strontium - The Missing Mineral for Strong Bones Strontium - The Missing Mineral for Strong Bones
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Complete and Natural Menopause Relief Complete and Natural Menopause Relief

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map