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Protecting The Lining Of Your Joints

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By ArthritisSupport Staff • • March 1, 2000

In order for osteoarthritis to be treated effectively, the cartilage and synovial fluid in the joint must be protected against further destruction. At the same time, it is desirable to stimulate anabolic restoration of joint cartilage and synovial fluid. Chondroprotective agents protect and restore joint cartilage by:

Supporting and enhancing anabolic chondrocyte synthesis.
Supporting or enhancing the synthesis of synovial fluid, which is required to lubricate the joint.
Inhibiting free radical enzymes and autoimmune processes that degrade joint cartilage.
Removing blockages in blood vessels leading to the joint.
Chondroprotective agents are compounds the body manufactures naturally in order to regenerate cartilage and healthy joint function. Aging and trauma disrupt the body's ability to use its own chondroprotective agents, which has led to an epidemic of arthritis throughout the world.


Glucosamine is used extensively in Europe to treat osteoarthritis. Numerous published studies document glucosamine's ability to function as a chondroprotective agent.

Glucosamine provides the raw material needed for chondrocytes to regenerate cartilage. A glucosamine deficiency caused by aging and/or trauma leads to osteoarthritis. The oral consumption of glucosamine salts provides the raw material needed for joint cartilage synthesis and repair.

In nine European studies, the oral administration of glucosamine produced major reductions in joint pain, joint tenderness and joint swelling. Improvements in joint function and overall physical performance were noted in these studies compared to placebo and/or the drug ibuprofen. While ibuprofen worked faster than glucosamine in relieving pain, glucosamine imtributed in the joint cartilage matrix

While the studies show that glucosamine takes 4-10 weeks to produce noticeable results, the new arthritis formula discussed in this article has been producing noticeable reductions in inflammation and pain in most arthritis patients in less than two weeks! This new formula (patent pending) includes two forms of glucosamine, along with EPA, DHA and GLA essential fatty acids.


The Chondroitin Sulfates

The chondroitin sulfates provide the structural components of the cartilage found in the joint. Chondroitin sulfate is a constituent of shark cartilage, which helps to explain the beneficial effects that shark cartilage produces in arthritis patients. The chondroitin sulfates have been tested extensively in humans with outstanding success as anti-atherosclerotic agents. The FDA has ruled, however, that, since each chondroitin sulfate molecule is different than all other molecules, which makes it impossible to produce a precisely standardized product, it cannot be approved as a therapy. Nevertheless, research studies have provided much useful data on the safety and effectiveness of chrondroitin sulfates in arthritis patients.

When intramuscular injections of chondroitin sulfates were given to arthritis patients, there were major reductions in joint pain and increases in joint function. Chondroitin sulfates inhibit free radicals that degrade joint cartilage and collagen. Chondroitin sulfates also improve blood circulation to joints, which enables antioxidants and glucosamine to enter inflamed joints to stimulate the repair process required for the regression of osteoarthritis.

Source: The Life Extension Foundation.

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