ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Cognitive Impairment II

Top 3 Nutrients to Detox the Liver and Soothe Digestion

Natural Bladder Control, Go Less and Live More

Study bodes well for low-carb eaters

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Omega Fix for Obesity: How the Right Fats Fight Fat

Potential of Quercetin in the Treatment of Melanoma

How Pomegranate May Protect Against Cancer

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Trimming the spare tire: Canola oil may cut belly fat

Print Page
Email Article

Nefazodone for patients with Chronic Fatigue Syndrome (CFS)

  [ 82 votes ]   [ Discuss This Article ] • April 10, 1999

OBJECTIVE: Patients with chronic fatigue syndrome (CFS)
present with a variety of musculoskeletal, neurocognitive,
sleep disturbance and mood symptoms. An open evaluation of the
clinical utility of the novel antidepressant compound,
nefazodone, was completed.

METHOD: Ten patients with CFS
presenting for assessment by a specialist psychiatrist were
treated with nefazodone. Patients treated within this
specialist service are also advised to engage in appropriate
behavioural and sleep-wake cycle strategies to improve their
level of functioning.

RESULTS: Of the 10 patients, eight (80%)
reported at least some improvement in the key symptom of
fatigue, with four (40%) reporting moderate or marked symptom
relief. Additionally, sleep disturbance and mood were both
moderately or markedly improved in seven (70%) and eight (80%)
of the patients, respectively. Five of the patients (50%)
achieved at least a moderate improvement in overall functional
outcome and were able to return to work or their previous
level of role function. The mean dose of nefazodone was 370
mg/day (range = 200-800 mg), with a strong preference for
nocturnal dosing. Seven of the patients had previously failed
to respond to moclobemide, while seven had previously failed
to respond to conventional antidepressant therapy.

Nefazodone appears to be worthy of further systematic
investigation in patients with CFS. Given its effects on
sleep, mood and anxiety symptoms, it may have particular
advantages in patients with this disorder.

Hickie I

Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Energy NADH™ 12.5mg FibroSleep™

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map