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Chronic Fatigue Syndrome (CFS): reviewing the research findings

  [ 74 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 10, 1999


Source: Ann Behav Med 1999 Summer;21(3):258-71

This article reviews the current state of research in chronic
fatigue syndrome (CFS). The evolving definition, prevalence,
and prognosis of this controversial illness are presented. We
review studies examining psychiatric, personality, and
psychosocial etiology for CFS. The evidence for
pathophysiology in CFS is also presented, and studies
investigating viral, immune, neuroimaging, neuroendocrine, and
central and autonomic nervous system abnormalities in CFS are
assessed. Current evidence indicates that CFS is
multi-determined and heterogeneous and that subgrouping
patients according to factors such as psychiatric state and
symptom onset may be fruitful. The current state of treatment
for CFS is reviewed, and the challenges for research aimed at
resolving this prototypical mind/body problem are discussed.

Johnson SK, DeLuca J, Natelson BH




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