ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

All About Ginkgo Biloba: Benefits of This Timeless Herbal Supplement

Yarrow Oil: Here's Why It Deserves a Place in Your First-Aid Kit

Trial Finds Reduction in Depressive Symptoms Following Magnesium Supplementation

Artificial sweeteners linked to risk of weight gain, heart disease and other health issues

Carnitine deficiency suggested as contributor to autism

Vitamin D supplement use associated with lower risk of breast cancer

Hop Oil: A Safe Sleep Aide

White Camphor Oil: The Purest Camphor Oil

Lutein — An Important Nutrient for Eye and Brain Health

 
Print Page
Email Article

Gene Sequence Linked to Women's risk of Alzheimer's Disease

  [ 31 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 26, 2001




Researchers recently reported women who have a particular genetic sequence appear to be at a higher risk of developing cognitive impairment and Alzheimer’s disease. This is according to a recent study presented at the Society for Neuroscience Annual Meeting.

Researchers at the University of California, San Francisco (UCSF), and the Veterans Affairs Medical Center (SFVAMC) have shown that these inherited sequences can create small differences in the receptor that binds estrogen molecules together. These receptors were linked with increased risk of Alzheimer’s disease, as well as a decline in performance on cognitive function tests over several years, said lead author Kristine Yaffe, MD, chief of geriatric psychiatry at SFVAMC, and UCSF assistant professor of psychiatry, neurology and epidemiology.

The study, which followed more than 2,800 women over roughly seven years, found that women with the high risk polymorphism were about 30 to 40 percent more likely to either suffer a major decline in test scores, or be diagnosed with Alzheimer’s disease.
So far, there’s no clear explanation for how these very small differences in the estrogen receptor gene actually influence the fate of women’s brains, Yaffe said. A few studies suggest that the polymorphisms may change the function of the receptor.

“In this study of older women, there wasn’t that big a difference in the initial cognitive scores. But over time, the women with these certain sequences had much more cognitive impairment. And they also had a much higher risk of being diagnosed with Alzheimer’s disease,” she said.

The researchers focused on two regions of the estrogen receptor gene that vary greatly from person to person. These gene regions, generally known as polymorphisms, had previously been linked to risks of osteoporosis, endometriosis and breast cancer, Yaffe said.

The estrogen receptor gene is only one of many that are likely to influence the risk of Alzheimer’s disease, Yaffe said. “We know about several genes that are linked to Alzheimer’s or appear to be, but it’s estimated that we have only found about 50 percent of these genetic risk factors,” she said.

Previous studies have shown that estrogen and its receptors play a major role in women’s brains. “We know there are estrogen receptors throughout the brain, particularly in the areas involved in learning and memory,” Yaffe said. Also, estrogen therapy after menopause appears to protect women from cognitive decline, she said.



Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Energy NADH™ 12.5mg FibroSleep™


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
Strontium - The Missing Mineral for Strong Bones Strontium - The Missing Mineral for Strong Bones
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map