ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Cognitive Impairment II

Top 3 Nutrients to Detox the Liver and Soothe Digestion

Natural Bladder Control, Go Less and Live More

Study bodes well for low-carb eaters

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Omega Fix for Obesity: How the Right Fats Fight Fat

Potential of Quercetin in the Treatment of Melanoma

How Pomegranate May Protect Against Cancer

Trimming the spare tire: Canola oil may cut belly fat

 
Print Page
Email Article

Duke Researchers Identify Age at Onset Genes for Alzheimer's and Parkinson's Disease

  [ 80 votes ]   [ Discuss This Article ]
www.ProHealth.com • March 11, 2002




Duke University Medical Center researchers have identified a group of chromosomes that could be responsible for controlling the onset of Alzheimer's or Parkinson's diseases.

The finding is significant because until now, geneticists have focused on finding individual genes that control the risk of developing a disease. However the age at which genetically-predisposed individuals develop symptoms of the disease is equally important. This is according to a study published in the April 2002 issue of American Journal of Human Genetics.

"Risk is only one mode of genetic expression. Age at onset of disease can also be genetically influenced. Understanding the regulation of onset will open new avenues of research that could one day make it possible to delay onset beyond an individual's normal lifespan," said Margaret Pericak-Vance, Ph.D., director of the Center for Human Genetics at Duke and principal investigator of the study.

The Duke research team conducted a genetic screening of 449 families that have multiple members diagnosed with Alzheimer's disease, and 174 families with multiple family members that are diagnosed with Parkinson's disease.

The age of onset of Alzheimer's disease is generally considered the time at which an individual begins to suffer short-term memory loss or disorientation in a manner serious enough to interfere with daily activities. The average age at onset for individuals in the study with Alzheimer's disease was 72.8 years old and 60.1 years old for Parkinson's disease.

Clinically, a significant number of Alzheimer's disease patients develop signs of Parkinson's disease, such as rigidity and gait abnormalities.

Past research by Duke and other researchers show that chromosome 10 could contain a risk gene for Alzheimer's disease. The new Duke research shows that chromosome 10 could contain an age at onset gene that affects both Alzheimer's and Parkinson's diseases. They also identified strong evidence for an age at onset gene for Parkinson's disease on chromosome 1.

"We tested the hypothesis that in some cases the same gene controls onset in two distinct neurodegenerative disorders that share some common features: Alzheimer's disease and Parkinson's disease. We found evidence supporting this hypothesis on chromosome 10," Pericak-Vance said.

Researchers also found evidence for age at onset linkage to chromosomes 4 and 8, however, the linkage was not as statistically significant.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map