ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Missing protein explains link between obesity, diabetes

Fish oil use associated with brain volume preservation

The Brain Boosting and Fatigue Fighting B-12

Genetic basis for distinct type of autism uncovered

Genetic study suggests causal link between vitamin D deficiency and hypertension

Unsuspected aspect of immune regulation revealed: Role of B cells

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

Explaining 'Healthy' Obesity

Sinus Congestion and Sinusitis, Healing Naturally

In the gut, immunity is a two-way street

 
Print Page
Email Article

Malic Acid: For Muscle Pain and Stiffness

  [ 66 votes ]   [ Discuss This Article ]
By Source: Health Watch • www.ProHealth.com • July 1, 1997


Fibromyalgia Syndrome (FMS) is a condition characterized by generalized musculoskeletal pain, aches, stiffness, and tenderness at specific sites. One of the primary and most debilitating symptoms of FMS is muscle pain and stiffness.

Researchers believe that this pain is caused by a local hypoxia of the muscles. Hypoxia refers to a low level of oxygen in the muscle, which leads to muscle tissue breakdown and mitochondrial damage. It has been hypothesized that in hypoxic muscle tissue, glycolysis is inhibited. This leads to a reduction of ATP synthesis. ATP is the body's main source of biochemical energy. As a result, the body begins to break down muscle proteins into amino acids to be utilized for ATP synthesis. This breakdown of muscle tissue is thought to be the cause of the muscle pain characteristic of FMS.

Leading FMS researchers and physicians such as 1. Jon Russell, M.D., Ph.D. prescribe malic acid as part of the multi- modal treatment plan for FMS, specifically for symptoms of hypoxia. In recent research at the University of Texas at San Antonio, malic acid was an element of the treatment program that showed improvement with FMS symptoms such as muscle pain.

Malic acid is a nutrient derived from fruit; it is also synthesized in the body through the citric acid cycle. It is involved in the production of energy in the body during aerobic and anaerobic conditions. It is capable of reversing the inhibition of glycolysis due to hypoxia. It removes accumulated reducing agents that build up during anaerobic conditions which inhibit glycolysis. This restores the production of ATP, thereby increasing available energy to the body. The body then no longer needs to break down muscle for ATP synthesis, which means that pain can be alleviated. Malic acid can thus alleviate pain and stiffness in FMS patients.








Discuss This Article Post a Comment 




[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
The Curcumin Revolution: The Curcumin Revolution: "Golden" Ticket to Better Health
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing