ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

The Significance of Selenium

Print Page
Email Article

The Changing Face of Severe Asthma: Boys in Childhood and Women as Adults

  [ 119 votes ]   [ Discuss This Article ] • October 15, 2003

Almost two out of three children with severe asthma are boys. But women account for more than two out of three adults with severe asthma. And no one really knows why. Those are some of the most striking results of a cross-sectional study of severe asthma by researchers from National Jewish Medical and Research Center being published in the October issue of the journal Chest. The research team, led by Joseph Spahn, M.D., also found that children with severe asthma had surprisingly good airflow in and out of their lungs, which could lead to misdiagnosis and undertreatment of seriously ill patients.

"Our findings highlight many of the significant differences between severe asthma in children and adults," said Dr. Spahn. "We hope they will spur further research that can lead to a better understanding and better treatment of this disease."

People with severe asthma, whose asthma remains uncontrolled in spite of high doses of medication, represent 5 percent to 10 percent of the estimated 20 million asthma patients in the United States. But they are important in terms of suffering, medical costs and difficulty finding effective treatments. Dr. Spahn and his colleagues examined a variety of demographic and biological data for 275 patients with severe asthma who had been referred to National Jewish.

Physicians have suspected that severe asthma differs considerably from childhood to adulthood, and indeed that turned out to be the case. The greatest difference was the male-to-female ratio. Males accounted for 62% of the patients under age 18. But 68% of the severe asthma patients over 18 were female. A similar situation has been noted in mild and moderate asthma, but not in patients with severe asthma.

"There has been speculation that a woman's hormones or possibly a difference in the size of male and female lungs play a role in this changing pattern of asthma prevalence, but no one really knows for sure why it occurs," said Dr. Spahn. "If we could learn why, we might gain valuable insight that could help us better treat all our asthma patients."

Dr. Spahn and his colleagues also found that children with severe asthma have deceptively good lung function. The amount of air a person can exhale in a second, known as forced expiratory volume in one second or FEV1, is one of the primary measures used to diagnose and categorize a patient's asthma. Patients are deemed to have severe asthma when their FEV1 is less than 60 percent of the average value for healthy people of their size and age.

The adults in Spahn's study had an average FEV1 that was 57 percent of the healthy average. Children in the study, however, averaged an FEV1 of 74 percent of the healthy average, with many exceeding 90 percent. Although other symptoms, such as medication use and history of asthma attacks, clearly put them in the severe category, the FEV1 results alone would have indicated that more than 40 percent had mild asthma and only 28 percent severe disease.

"The good news is that children have significantly less impaired lung function than do adults with asthma," said Dr. Spahn. "The bad news is that existing guidelines do not reflect this fact, and physicians may be mistakenly reassured by normal or near normal lung function readings in their pediatric patients. As a result, they may fail to appreciate the severity of their patients' asthma and undertreat them."

The study also indicates that patients whose asthma began in childhood rapidly lose lung function through adolescence then level off to a more moderate decline as they reach adulthood. Patients whose asthma began in adulthood, however, lose lung function almost immediately.

"Child-onset and adult-onset asthma may be two distinct forms of the disease, one that is slowly progressive over time and another that is associated with significant loss of lung function very shortly after onset," said Dr. Spahn.

Source: National Jewish Research and Medical Center.

Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol
Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10 Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map