ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

The Significance of Selenium

Print Page
Email Article

Arthritis Study Shows Celebrex Easiest on Stomach

  [ 139 votes ]   [ Discuss This Article ]
By ArthritisSupport Staff • • June 2, 2000

Celebrex, a drug used to reduce pain and inflammation associated with arthritis, causes fewer gastrointestinal upsets than non-steroidal anti-inflammatory drugs (NSAIDs).

According to Dr. Jay Goldstein of the University of Illinois at Chicago, a category of drugs called COX-2 inhibitors work as well as or better than NSAIDs (such as ibuprofen, indomethicin, naproxen) to control some of the symptoms associated with arthritis. In the study, patients who used Celebrex, or its generic counterpart celecoxib, were free from the side effects connected with use of NSAIDs despite the fact that patients received four times more than the highest recommended dose.

The Long-term Arthritis Safety Study (CLASS) studied Celebrex and its side effects over a 13-month period. Nearly 6000 patients with osteoarthritis (OA) and over 2000 with rheumatoid arthritis (RA) took daily doses of three drugs: 2400 mg of ibuprofen (brand names of Motrin, Advil, etc.), 150 mg of diclofenac (brand names of Volteren) and 800 mg of celecoxib (brand name Celebrex.)

Those taking Celebrex had fewer ulcer complications, blood loss and GI problems. The benefits to drug users were clear. "The findings are strong and convincing," said Goldstein, medical director of clinical resource management of the University of Illinois Hospital Clinics in Chicago and a member of both the American College of Gastroenterologists and the American Society for Gastrointestinal Endoscopy.

"Many physicians feel that patients requiring short-term administration of traditional NSAIDs are not at risk for a serious gastrointestinal event," Goldstein added. "These results tell a different story, highlighting that many of the events caused by traditional NSAIDs occurred within the first few weeks."

Celebrex resulted in fewer side effects.

The groups taking NSAIDs had higher incidence of GI bleeding than those taking Celebrex. And despite the recent debates about cardiovascular safety and COX-2 Inhibitors, celecoxib patients had no increase in cardiovascular events (stroke, MI) compared to those using NSAIDs.

A separate study found that celecoxib could be taken at four times the maximum dose without serious side effects. Ulcers are a complication that can also arise from using NSAIDs. In the CLASS study, those using Celebrex did not develop ulcers.

Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
Safely Burn Away Body Fat Safely Burn Away Body Fat

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map