Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

Greater intake of dietary omega-3 fatty acids associated with lower risk of diabetic retinopathy

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Best Herbs to Help With Insomnia

Nature Heals

Meet the ProHealth Editors

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

 
Print Page
Email Article

Anticardiolipin antibodies in childhood rheumatic disorders

  [ 16 votes ]   [ Discuss This Article ]
By Gedalia A, Molina JF, Garcia CO, Doggett S, Espinoza LR, Gharavi AE • www.ProHealth.com • January 6, 1998


Anticardiolipin antibodies (aCL) have been reported to occur in a
wide variety of autoimmune and non-autoimmune disorders in
adults. Our objective was to investigate the prevalence and
isotype distribution of aCL and its relationship with the
features of antiphospholipid syndrome (APS) in childhood
rheumatic disorders.

Between November 1995 and May 1996, all patients
who visited our paediatric rheumatology clinic whose
guardians signed a consent form participated in the study. The
study population included 106 patients (36 systemic lupus
erythematosus (SLE), 28 juvenile rheumatoid arthritis (JRA),
11 fibromyalgia, 7 sarcoidosis, 5 dermatomyositis, 3 rheumatic
fever (RF), 3 vasculitis, 2 scleroderma, and 11
miscellaneous). aCL measurements were performed by enzyme
linked immunoabsorbent assay (ELISA). All patients were
carefully evaluated for symptoms and signs of APS. Eighteen of
the 106 patients (17%) were tested positive for one or more of
the three aCL isotypes. In SLE, aCL were found positive in 13
of 36 (37%); in JRA 2 of 28 (7%); in sarcoidosis 2 of 7; and
in RF 1 of 3. aCL of IgG isotype were found positive in 16
patients (11 SLE, 2 sarcoidosis, 2 JRA, and 1 RF). This
isotype was usually detected at low titers (16-24 GPL). aCL of
IgM isotype were found positive in five patients (2
sarcoidosis, 2 SLE, 1 JRA), and aCL of IgA isotype were found
positive in only three patients (2 SLE, 1 sarcoidosis).


Clinical features of APS were rarely seen in our SLE
population and were not associated with the presence of aCL.
None of the patients in the other groups exhibited any
clinical manifestations of APS. In conclusion, aCL were found
in 37% of our childhood SLE patients as compared with only 7%
in JRA. These were mostly aCL of IgG isotype of low titers and
therefore were not associated with the main features of APS.
Prospective studies with a larger sample size may be needed to
ascertain the exact prevalence and clinical significance of
aCL in childhood-onset SLE.




Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
How Glutathione Can Save Your Life How Glutathione Can Save Your Life
Relief for Dry, Itchy Skin Caused by Fibromyalgia Relief for Dry, Itchy Skin Caused by Fibromyalgia
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map