ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

16 Tips from 16 Years Sick

On-and-off fasting helps fight obesity, study finds

Fibromyalgia Fare Fit for All Seasons

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Higher vitamin D levels associated with less severe disease in NAFLD patients

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

How zinc helps fight esophageal cancer

Low vitamin D levels predict ED in diabetics

What Benefits Can You Get From High-Quality Whey Protein?

 
Print Page
Email Article

Elements of green tea prevent HIV from binding to human T cells

  [ 27 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 10, 2003


New research from the November Journal of Allergy and Clinical Immunology

The major component of green tea prevents the binding of HIV to human T cells, the first step in HIV infection, according to a study and an accompanying editorial published in the November 2003 Journal of Allergy and Clinical Immunology (JACI). The JACI is the peer-reviewed journal of the American Academy of Allergy, Asthma & Immunology (AAAAI).

Green tea is the nonoxidized, unfermented product of the leaves from the evergreen plant, Camellia sinensis. It is made up of catechins, the most abundant of which is Epigallocatechin Gallate (EGCG). It is believed that EGCG is responsible for the vast array of presumed health benefits green tea possesses, such as the prevention of cancer and cardiovascular disease. Several studies have reported that EGCG may also have a protective effect against HIV infection.

Kuzushige Kawai, MD, and colleagues from the University of Tokyo demonstrated in laboratory studies that EGCG blocked the binding of HIV envelope glycoprotein to human CD4 molecules on human T cells. The CD4 molecule acts as a binding target for HIV vesicles and plays an important role in the aggressive infection process.

Researchers found that EGCG showed a strong affinity for the CD4 molecule, and by binding them, could effectively prevent the binding of the HIV glycoprotein envelope. These findings open new doors for the clinical application of EGCG as a new anti-HIV drug.

Further research into the potential preventative effects of the green tea catechin EGCG on HIV infection is being conducted by researchers at the National Center for Macromolecular Imaging at Baylor College of Medicine, Houston, Texas, and the Department of Molecular Biology and Biotechnology at the University of Sheffield, Sheffield, England. In an editorial accompanying the Kawai study, William T. Shearer, MD, PhD, FAAAAI, and colleagues from Baylor report on the use of advanced computer programs to better define the nature and power of the binding effects of EGCG to the CD4 molecule.

"It might be possible to locate the precise EGCG binding spot on the CD4 molecule and compare that spot to where the HIV glycoprotein normally binds, in an attempt to explain the exciting discovery of Dr. Kawai," said Dr. Shearer. "Molecular modeling of a drug form of EGCG for HIV infection might be a further development of these investigations."

The study and the accompanying editorial are the first to describe the inhibitory effect of green tea catechin in the attachment of HIV to human T cells and offer a new perspective for the treatment of the life-threatening disease.

Researchers do not suggest the use of green tea to counter HIV infection or as an alternative therapy to current anti-viral agents now used.

The concentrations of EGCG used to demonstrate these inhibitory effects in laboratory studies are many times over the blood concentration that could be achieved by normal green tea consumption. However, the current findings call for additional research into the clinical application of green tea catechin as an anti-HIV drug.

The AAAAI is the largest professional medical specialty organization in the United States representing allergists, asthma specialists, clinical immunologists, allied health professionals and others with a special interest in the research and treatment of allergic disease. Allergy/immunology specialists are pediatric or internal medicine physicians who have elected an additional two years of training to become specialized in the treatment of asthma, allergy and immunologic disease.



Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map