ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Meta-analysis links vitamin D deficiency with increased risk of mortality during 10.5 year median pe...

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Valerian Root Help You Sleep Better?

Can Ginkgo Give Your Brain a Boost?

Fighting Statin-Induced Diabetes with CoQ10

Eight servings of veggies a day is clearly best for the heart

The Many Wonders of Calming Sandalwood Oil

Curcumin — A Novel Treatment Alternative for Depression

 
Print Page
Email Article

Increased 24-hour urinary cortisol excretion in patients with post-traumatic stress disorder & patients with major depression, but not in patients with fibromyalgia (FM)

  [ 49 votes ]   [ Discuss This Article ]
By Maes M, Lin A, Bonaccorso S, van Hunsel F, Van Gastel A, Delmeire L, Biondi M, Bosmans E, Kenis G, Scharpe S • www.ProHealth.com • October 6, 1998


There is now firm evidence that major depression is
accompanied by increased baseline activity of the
hypothalamic-pituitary-adrenal (HPA) axis, as assessed by
means of 24-h urinary cortisol (UC) excretion. Recently, there
were some reports that fibromyalgia and post-traumatic stress
disorder (PTSD), two disorders which show a significant
amplitude of depressive symptoms, are associated with changes
in the baseline activity of the HPA axis, such as low 24-h UC
excretion . The aim of the present study was to examine 24-h UC
excretion in fibromyalgia and PTSD patients compared to normal
controls and patients with major depression. In the three
patient groups, severity of depressive symptoms was measured
by means of the Hamilton Depression Rating Scale (HDRS) score.
Severity of fibromyalgia was measured using a dolorimetrically
obtained myalgic score, and severity of PTSD was assessed by
means of factor analytical scores computed on the items of the
Composite International Diagnostic Interview (CIDI), PTSD
Module. Patients with PTSD and major depression had
significantly higher 24-h UC excretion than normal controls
and fibromyalgia patients. At a threshold value of > or = 240
micrograms/24 h, 80% of PTSD patients and 80% of depressed
patients had increased 24 h UC excretion with a specificity of
100%. There were no significant differences in 24-h UC
excretion either between fibromyalgia patients and normal
controls, or between patients with major depression and PTSD
patients. In the three patient groups, no significant
correlations were found between 24-h UC excretion and the HDRS
score. In fibromyalgia, no significant correlations were found
between 24-h UC excretion and the myalgic score. In PTSD, no
significant correlations were found between 24-h UC excretion
and severity of either depression-avoidance or anxiety-
arousal symptoms. In conclusion, this study found increased
24-h UC excretion in patients with PTSD comparable to that in
patients with major depression, whereas in fibromyalgia no
significant changes in 24- h UC were found.




Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Energy NADH™ 12.5mg Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map