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Selenium status in fibromyalgia (FM)

  [ 41 votes ]   [ Discuss This Article ]
By Reinhard P, Schweinsberg F, Wernet D, Kotter I • • August 5, 1998

Fibromyalgia (FM) is a chronic musculoskeletal pain syndrome
of unknown etiology. The serum concentration of selenium (Se)
was measured in 68 consecutive patients (nine male, mean age:
47 years; 59 female, mean age 49 years) with FM. The age- and
sex-matched control group included 97 female healthy blood
donors (mean age 46 years). The method is based on
high-performance liquid chromatography (HPLC) involving
detection of the fluorescent diaminonaphthalene (DAN) derivate
of selenite. There was a statistical significant difference (P
< 0.05) in serum Se between control (median 77 microg/l;
range: 50-118 microg/l) and patients (median 71 microg/l;
range: 39-154 microg/l) groups in the region of Tubingen,

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