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Alteration of spatial-temporal parameters of gait in Chronic Fatigue Syndrome (CFS) patients

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By Saggini R, Pizzigallo E, Vecchiet J, Macellari V, Giacomozzi C • www.ProHealth.com • January 21, 1998


Chronic Fatigue Syndrome (CFS) has been widely studied and a
lot of information is available in the literature regarding
the immunological, virological, neuroendocrinal and
psychiatric aspects of the disease, but its aetiology is still
poorly understood. Great attention has also been paid to the
alteration of the muscular function caused by CFS. The aim of
the present work was to study CFS patients' gait in order to
find out objective measures which can better characterize the
pathology. Spatial and temporal parameters of gait were
collected from a group of 12 CFS informed volunteers by using
the typical instrumentation of movement analysis, and raw data
were statistically elaborated. Comparisons with reference data
from a population of healthy subjects revealed significant
abnormalities in the symmetry indices of the bilateral
parameters and in the linear relationships among parameters,
and between these parameters and the physical characteristics
of the patients. Interestingly, the abnormalities were present
as from the beginning of the gait, which indicates that they
are unlikely to be caused by the rapid increasing fatigue.
This strengthens the hypothesis of a direct involvement of the
central nervous system (CNS) in the onset of the disease.




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