ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Eat More Yogurt and Avoid Osteoporosis

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Curcumin, resveratrol, ursolic acid show promise against prostate cancer

Higher omega 3 levels linked to improved brain blood flow

Olive oil compound could help protect against brain cancer

Probiotic use linked to improved symptoms of depression

How Fish Oil Benefits Heart Disease Patients with Depression

 
Print Page
Email Article

New study findings showed Aricept® effective in treating patients with severe Alzheimer's disease

  [ 113 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 4, 2003


Severe Alzheimer's disease (AD) patients treated with Aricept ® (donepezil HCl tablets) showed significant improvement in global function, cognition, behavior, and activities of daily living versus placebo, according to new data from a subset analysis of the Moderate to Severe Alzheimer's Disease Study (MSAD), previously published in Neurology in August 2001.

These data, which were presented at the American Academy of Neurology (AAN) 55th Annual Meeting, demonstrated that Aricept ® provided significant benefits versus placebo in everyday tasks, as well as in behavioral symptoms associated with AD. These findings suggest Aricept ® may provide important benefits for patients with advanced AD.

"The results of this trial indicate that the benefits of Aricept ®, which have been reported in clinical trials of mild to moderate AD, may also extend into the severe AD stage," said Howard Feldman, MD, UBC Hospital, Clinic for Alzheimer's Disease and Related Disorders, Vancouver, British Columbia. "These findings are meaningful for patients when treatment is started even in the later stage of the disease."

In this analysis, 145 patients with severe Alzheimer's disease were randomized to receive either Aricept ® (n=72), 5 mg once daily for the first 28 days and 10 mg once daily thereafter based on the clinicians' judgment, or placebo (n=73). Baseline demographics, including age and sex, were similar between the Aricept ® and placebo groups.

The study enrolled patients residing in the community or in assisted living settings. Patients requiring total nursing care were ineligible. The mean standardized Mini/Mental State Examination (sMMSE) score at baseline was 9.0 for the Aricept ® group and 8.9 for the placebo group. Patients were assessed at Weeks 4, 8, 12, 18, and 24. Consistent benefits were found for Aricept ® across the full range of measures of patient outcomes – global function, cognition, behavior, and activities of daily living .

Aricept ®-treated patients showed statistically significant improvement or remained at or near baseline throughout the study on measure of global function, while placebo-treated patients showed functional decline.

Patients showed statistically significant overall cognitive improvement versus placebo, showed statistically significantly less decline compared with placebo-treated patients on activities of daily living, and showed statistically significant overall improvement versus placebo in behavioral disturbances associated with Alzheimer's.



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor® Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
The Genetic Mutation That May Compromise Your Health - And What to Do About It The Genetic Mutation That May Compromise Your Health - And What to Do About It
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map