ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

Artificial sweeteners linked to risk of weight gain, heart disease and other health issues

All About Ginkgo Biloba: Benefits of This Timeless Herbal Supplement

Yarrow Oil: Here's Why It Deserves a Place in Your First-Aid Kit

Vitamin D supplement use associated with lower risk of breast cancer

Carnitine deficiency suggested as contributor to autism

Hop Oil: A Safe Sleep Aide

Lutein — An Important Nutrient for Eye and Brain Health

White Camphor Oil: The Purest Camphor Oil

Taurine: Facts About This Crucial Amino Acid

 
Print Page
Email Article

New Findings Show Reminyl® Slows Cognitive Decline By 60 % in Alzheimer's

  [ 167 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 23, 2003


Treatment with Reminyl® (galantamine hydrobromide) may slow the progression of mild to moderate Alzheimer's disease by 50 to 60 percent when used continuously for 48 months, according to a new study presented at the 156th Annual Meeting of the American Psychiatric Association.

The data showed that more than 12 percent of patients did not deteriorate at all. While the remaining patients showed varying degrees of deterioration, the investigators concluded that it was less than would be expected in an untreated Alzheimer's disease population. With 240 patients evaluated over the full 48 months, this is the largest long-term study of its kind.

"This study provides additional evidence that long-term therapy with Reminyl can have long-term benefits, by delaying the natural rate of decline," said Luc Truyen, M.D., Ph.D., Senior Director, Clinical Development, CNS, Johnson & Johnson Pharmaceutical Research & Development (J&JPRD), and a study co-author. "For participants in this four-year study, cognitive decline was significantly delayed compared to the natural rate of decline in untreated patients."

Dr. Truyen noted that Alzheimer's disease typically progresses over the course of 10 years, and that the data showed continuous benefit from Reminyl during the entire four-year period.

The study consisted of open-label extensions of two double-blind, placebo- controlled trials. Patients received 24 to 32 mg of Reminyl daily during the initial three to six month blinded portions of the research; during the open-label extensions, the 240 patients received 24 mg of Reminyl every day.

The research focused on patients' cognitive performance, which includes the ability to think, reason and learn. Among participants receiving Reminyl, scores on the cognitive portion of the Alzheimer's Disease Assessment Scale (ADAS-cog) deteriorated 12.8 points. This compares to an expected decline of 24 to 36 points for untreated patients, based on the Stern equation, a standard measurement of cognitive decline in people with Alzheimer's disease.

Reminyl is thought to inhibit an enzyme that breaks down acetylcholine -- a neurotransmitter in the brain that plays a key role in memory and learning. In addition, it is believed that Reminyl modulates the brain's nicotinic receptors, to which acetylcholine binds. The clinical significance of these mechanisms is unknown.

"These findings should give Alzheimer's disease patients and caregivers hope that the progression of symptoms in this disabling disorder can be slowed for many sufferers, an important consideration as families and patients focus on getting the most out of the time they have," said Gordon Wilcock, Professor of Care of The Elderly, University of Bristol, UK, and a study investigator.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Vitamin D3 Extreme™ Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map