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Genotoxicity & chronic health effects of automobile exhaust: a study on the traffic policemen in the city of Lanzhou

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By Zhao X, Niu J, Wang Y, Yan C, Wang X, Wang J • www.ProHealth.com • July 31, 1998


A study on the health and genotoxic effects of occupational exposure
to automobile exhaust was carried out among traffic policemen
in Lanzhou (China) in 1996. A total of 78 traffic policemen
working in the field was the exposed group, and 57 household
register policemen working in the office was the control
group. The health effects were evaluated by health
questionnaires. Significant differences were observed between
the exposed and control groups with respect to the morbidity
of rhinitis, pharyngitis, trachoma, syndrome of neurasthenia
and joint pain, apart from disorders in the digestive system.
The percentage of rhinitis and pharyngitis obtained in the two
groups was significantly higher among the smokers than among
the nonsmokers. The frequencies of micronuclei (MN) and
sister-chromatid exchanges (SCEs) were measured in peripheral
blood lymphocytes from the two groups of volunteers. Compared
with the control group, statistically significant increases of
MN and SCE were found for the exposed group. The increase in
the induction of MN and SCE among the traffic policemen and
household register policemen is enhanced further by smoking.




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