ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimm...

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Acupressure reduced fatigue in breast cancer survivors

Omega-3 fatty acid stops known trigger of lupus

What’s Fenugreek Good For?

Print Page
Email Article

Pathogenesis & management of delayed orthostatic hypotension in patients with Chronic Fatigue Syndrome (CFS)

  [ 49 votes ]   [ Discuss This Article ]
By De Lorenzo F, Hargreaves J, Kakkar VV • • August 15, 1997

The relationship between orthostatic hypotension and chronic fatigue
syndrome (CFS) has been reported previously. To study the
pathogenesis and management of delayed orthostatic hypotension
in patients with CFS, a case comparison study with follow-up
of 8 weeks has been designed.

A group of 78 patients with CFS (mean age 40 years;
49% men and 51% women), who fulfilled the
Centre for Disease Control and Prevention criteria were
studied. There were 38 healthy controls (mean age 43 years;
47% men and 53% women). At entry to the study each subject
underwent an upright tilt-table test, and clinical and
laboratory evaluation. Patients with orthostatic hypotension
were offered therapy with sodium chloride (1200 mg) in a
sustained-release formulation for 3 weeks, prior to
resubmission to the tilt-table testing, and clinical and
laboratory evaluation.

An abnormal response to upright tilt was observed
in 22 of 78 patients with CFS. After sodium chloride
therapy for 8 weeks, tilt-table testing was repeated
on the 22 patients with an abnormal response at baseline. Of
these 22 patients, 10 redeveloped orthostatic hypotension,
while 11 did not show an abnormal response to the test and
reported an improvement of CFS symptoms. However, those CFS
patients who again developed an abnormal response to tilt-test
had a significantly reduced plasma renin activity (0.79
pmol/ml per h) compared both with healthy controls (1.29
pmol/ml per h) and with those 11 chronic fatigue patients (1.0
pmol/ml per h) who improved after sodium chloride therapy (p =

In conclusion, in our study CFS patients who did not
respond to sodium chloride therapy were found to have low
plasma renin activity. In these patients an abnormal
renin-angiotensin-aldosterone system could explain the
pathogenesis of orthostatic hypotension and the abnormal
response to treatment.

Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map