ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Relief for IBS, Colitis, Crohn’s And More

B Vitamins May Protect Against Damaging Effects of Air Pollution, and Improve Cognition and Psychiat...

Can Magnesium Relieve Your Tinnitus?

Restless Leg Syndrome (RLS) - are you running a marathon each night?

Resveratrol Proven to Slow Brain Aging

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Fruits and vegetables' latest superpower? Lowering blood pressure

Neroli Oil: The Pleasantly Fragrant Citrus Oil

Prenatal vitamin D could help prevent autism in children

Restoring NAD+ could reduce DNA damage accumulation

 
Print Page
Email Article

Maas BiolAB: Cyclosporin Protects Brain Mitochondria at the 33rd Annual Society for Neuroscience Meeting

  [ 146 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 3, 2003


BIOWIRE2K

ALBUQUERQUE, N.M.--(BUSINESS WIRE)--Dec. 3, 2003--Maas BiolAB LLC and NeuroPharma AB Director of Research Eskil Elmer M.D., Ph.D., and research scientists Magnus Hansson M.D. and Roland Mansson M.D. exhibited and co-authored 3 poster presentations at the annual Society for Neuroscience Meeting in New Orleans, Louisiana. Two of the presentations were the result of research stemming from Maas BiolAB/NeuroPharma's expertise in mitochondrial neuroprotectants.

The research revealed that brain mitochondria are specifically and powerfully protected by cyclosporins, through cyclosporins' unique ability to block the formation of the mitochondrial permeability transition pore or "megapore". Blocking this mitochondrial megapore prevents the release of mitochondrial apoptosis factors that activate caspases and turn on neuron suicide genes. Cyclosporins protect damaged neurons from dying, and have been shown to be potent neuroprotectants in models of acute brain attack including stroke, traumatic brain and spinal cord injury, and also the chronic neurodegenerative diseases of Alzheimer's, Parkinson's, Huntington's and ALS.

The first presentation "Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition" demonstrated that cyclosporin protects metabolically active brain mitochondria in particular, information important to demonstrating the mechanism by which cyclosporin protects the brain.

The second presentation "Minocycline does not inhibit calcium-induced mitochondrial permeability transition" analyzed minocycline, a putative neuroprotectant drug, and found it not to be effective via the mitochondria "megapore". Minocycline was assessed using the rapid and reliable screening techniques developed by Maas/NeuroPharma scientists to evaluate series of novel potential mitochondrial neuroprotectants.

Maas BiolAB LLC is a privately held Swedish-American neuropharmaceutical corporation with world patents for cyclosporin neuroprotection based in Albuquerque, NM, USA. Maas BiolAB is developing cyclosporin drugs for the neurodegenerative diseases of Alzheimer's, Parkinson's, Huntington's and amyotrophic lateral sclerosis. NeuroPharma AB is a Maas corporate partner developing NeuroSTAT(TM), a proprietary, non-toxic intravenous cyclosporin product for traumatic brain injury, spinal cord injury and stroke. NeuroPharma AB is in the Scandinavian Medicon Valley biotechnology center of Lund, Sweden, with close ties to the Wallenberg Neuroscience Center at Lund University. For more information please visit www.maasbiolab.com .



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Vitamin D3 Extreme™ Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Clinically Studied Joint Relief Product for FM & ME/CFS Clinically Studied Joint Relief Product for FM & ME/CFS
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
How One Tiny Molecule Turned into One Huge Health Breakthrough How One Tiny Molecule Turned into One Huge Health Breakthrough

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map