ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

16 Tips from 16 Years Sick

Fibromyalgia Fare Fit for All Seasons

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Antioxidant treatment could halt neurodegeneration in early Parkinson's

Higher vitamin D levels associated with less severe disease in NAFLD patients

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

How zinc helps fight esophageal cancer

Everything You Need to Know About Black Cohosh

Low vitamin D levels predict ED in diabetics

 
Print Page
Email Article

Down Syndrome Study Reveals Possible Method for Detecting Initial Stages of Alzheimer’s

  [ 20 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 23, 2003


Brain scans show increased metabolism by neural cells when battling onset of degenerative disease

Irvine, Calif. -- UC Irvine College of Medicine researchers conducting the first longitudinal brain imaging study of adults with Down syndrome may have found a way to detect Alzheimer's disease before symptoms of dementia begin to set in.

In the study, brain scans of adults with Down syndrome showed increased metabolic activity in the temporal cortex – the same region of the brain where Alzheimer's disease commonly develops. The researchers speculate that Alzheimer's may begin with a similar metabolic increase, because Down syndrome often leads to dementia during adulthood

If so, a common PET scan procedure could allow early detection of Alzheimer's.

Study results appear in the Dec. 23 issue of Neurology.

According to Richard Haier, professor of pediatrics and principal investigator of the study, neurons work efficiently in normal brains, but in diseased brains, damaged neurons have to work harder to maintain their effectiveness, as revealed by the metabolic rate increases in Down syndrome brains. This damage most likely comes from the progressive accumulation of both senile plaques and neurofibrillary tangles, the two lesions associated with both Down syndrome and Alzheimer's. When the damaged neurons are ultimately destroyed by these lesions, the metabolic rate will decrease, as was observed in the Alzheimer's-diseased brains scanned for the study.

"These findings suggest that Down syndrome dementia and possibly Alzheimer's disease may begin when neuronal damage in the temporal cortex region reaches the point where increased metabolism can no longer compensate," Haier said. "But to confirm this, further imaging tests must be done on the Down syndrome people as dementia progresses."

Nearly 350,000 Americans have Down syndrome, which is a genetic disorder caused by the inheritance of three copies of the 21st chromosome. People with Down syndrome show some of the brain changes of Alzheimer's as early as age 12. Nearly all Down syndrome patients have the brain changes of Alzheimer's disease by age 40. Despite this, not all individuals with Down syndrome develop symptoms of the disorder.

The National Institute of Child Health and Development is providing funding for this study.

Dr. Michael Alkire, Nathan White, Melina Uncapher, Elizabeth Head, Dr. Ira Lott and Carl Cotman of UCI assisted Haier with the study.

About the University of California, Irvine: The University of California, Irvine is a top-ranked public university dedicated to research, scholarship and community. Founded in 1965, UCI has more than 23,000 undergraduate and graduate students and about 1,300 faculty members. The third-largest employer in dynamic Orange County, UCI contributes an annual economic impact of $3 billion.

UCI maintains an online directory of faculty available as experts to the media. To access, visit: www.today.uci.edu/experts.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map