ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Black Tea Is Great for Your Gut

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

 
Print Page
Email Article

Soy consumption could help prevent prostate cancer and male pattern baldness

  [ 50 votes ]   [ Discuss This Article ]
www.ProHealth.com • March 29, 2004


CINCINNATI --

A team of scientists has discovered that a little-known molecule created in the intestine when soy is digested is a natural and powerful blocker of a potent male hormone involved in prostate cancer and male pattern baldness. In fact, the molecule, equol, completely stops in its tracks the male hormone dihydrotestosterone (DHT), which normally stimulates prostate growth and causes male pattern baldness.

"This molecule is remarkable," says Kenneth Setchell, PhD, director of Clinical Mass Spectrometry at Cincinnati Children's Hospital Medical Center, who first identified equol in humans 20 years ago. "These findings are of immense clinical importance because blocking the action of the potent androgen (male hormone) DHT has been one of the holy grails of the pharmaceutical industry as a strategy for treating prostate cancer and other related diseases. This natural metabolite made from soy isoflavones, which are found in high amounts in soybeans, does this very effectively."

The study, which tested the response to equol in rats, was conducted at Colorado State University, Brigham Young University, and Cincinnati Children's and appears in the April edition of Biology of Reproduction. In recent years, the pharmaceutical industry has developed drugs that inhibit a certain enzyme that converts testosterone to DHT. Unfortunately, these drugs have side effects.

Equol, on the other hand, doesn't prevent DHT from being made but prevents it from functioning. It puts "handcuffs" on DHT, preventing it from binding to the androgen receptor and thereby preventing the prostate from growing. This may be particularly important for men who have been diagnosed with either an enlarged prostate (benign prostatic hyperplasia, or BPH) or cancer of the prostate. "Directly binding and inactivating DHT without influencing testosterone gives equol the ability to reduce many of the harmful effects of androgens without affecting the beneficial ones," said Robert J. Handa, PhD, senior author of the study and professor in the department of biomedical sciences at Colorado State's College of Veterinary Medicine.

"The novelty of equol is that it both inhibits androgen hormone and influences estrogen hormone action," adds Edwin Lephart, PhD, professor of physiology and developmental biology and director of the Neuroscience Center at Brigham Young University. "We do not know of any other molecule that possesses these important biochemical properties."

Two experiments demonstrated that injections of equol into male rats reduced the size of the prostate. In one study, the testes of male rats were removed, thereby eliminating all DHT production. When investigators injected DHT into rats, their prostates grew. When they gave rats equol, nothing happened at all. When they injected rats with both equol and DHT, the equol prevented the DHT from functioning as it normally would – as a stimulator of prostate growth. In other words, equol did not change hormone levels but completely blocked the effects of DHT in rats.

This could explain why men in Japan, who eat more soy than American men but suffer equally from BPH as they age, rarely go on to have prostate cancer, according to Dr. Setchell. Several human studies have demonstrated the advantages of eating soy in reducing the risk of prostate cancer. So far, research has established the relevance of DHT in the growth of male reproductive organs and, given the importance of DHT in the skin, it is possible that equol may offer a means of controlling hair loss and promoting healthy skin.

The researchers have initiated further studies of equol to assess its potential as a treatment for a variety of other androgen-mediated conditions. The team has filed patent applications on equol and hopes to commercialize the technology.

The lead author of the study was Trent Lund, assistant professor in the department of biomedical sciences at Colorado State.
Source: EurekAlert.org (this is a press release).



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Fighting Fatigue with Ground-breaking French Oak Wood Extract Fighting Fatigue with Ground-breaking French Oak Wood Extract
Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map