ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimm...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Omega-3 fatty acid stops known trigger of lupus

What’s Fenugreek Good For?

Print Page
Email Article

Possible deficiencies of pain modulation in fibromyalgia (FM)

  [ 27 votes ]   [ Discuss This Article ]
By Lautenbacher S, Rollman GB • • September 12, 1997

OBJECTIVE: To examine possible deficiencies in endogenous pain
modulating mechanisms in fibromyalgia patients compared with
matched pain-free control subjects.

DESIGN/SUBJECTS/METHODOLOGY: Pain reduction was investigated
in 25 female patients with fibromyalgia and 26 age-matched
healthy women using the diffuse noxious inhibitory controls
(DNIC) paradigm. Tonic thermal stimuli at painful and
nonpainful intensities, tailored to individual heat pain
thresholds, were employed to induce pain inhibition. The
anticipated effect was assessed by measuring the electrical
pain threshold and detection threshold, using a double
staircase method. Only nontender control points were
stimulated (thermode on the foot, electrodes on the inner

RESULTS: The patients with fibromyalgia had
significantly lower heat pain thresholds than the healthy
subjects, but similar electrical detection and pain
thresholds. The repeatedly applied electrical stimuli resulted
in a degree of perceptual adaptation that was similar between
the two groups. However, concurrent tonic thermal stimuli, at
both painful and nonpainful levels, significantly increased
the electrical pain threshold in the healthy subjects but not
in the fibromyalgia patients. The electrical detection
threshold was not affected in either group.

modulation, produced by a concurrent tonic stimulus in healthy
persons, was not seen in the fibromyalgia group. The patients
either had deficient pain modulation or were unable to
tolerate a tonic stimulus intense enough to engage a
modulatory process. It remains to be established whether the
pain reduction found in the healthy subjects was the
conventional DNIC effect, another effect (e.g., distraction),
or a combination of both.

Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™ Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health
Live Without Anxiety or Stress Live Without Anxiety or Stress
Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7
Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map