ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Tea drinkers have lower glaucoma risk

Soy, cruciferous vegetables could help lower breast cancer treatment side effects

Basic Aromatherapy to Help Balance and Calm

The Long-Term Benefits of Drinking Oolong Tea

Why You Should Try This Sweet-Smelling and Health-Boosting Essential Oil

Wonderful White Tea: A Drink Fit for an Emperor

Arnica: This Powerful Herb Promotes Various Kinds of Healing

Chamomile Tea: Why This Ancient Therapeutic Drink Still Stands Out Today

Get ‘Hooked’ on Cat’s Claw: The Many Benefits of This Amazonian Herb

Try Apple Cider Vinegar and Black Cumin Oil as Your Go-To Salad Dressing

 
Print Page
Email Article

Low Vitamin B12 Linked to Poor Memory and Higher Alzheimer's Risk

  [ 249 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 12, 2004


Low vitamin B12 is associated with poorer memory in older people with high risk for Alzheimer's: Large-scale Swedish study reveals how nutrition and genes interact to render people vulnerable to cognitive problems in old age WASHINGTON --

Among healthy people over the age of 75 who have the genotype associated with higher risk for Alzheimer's, low levels of vitamin B12 are associated with significantly worse performance on memory tests. This finding is published in the April issue of Neuropsychology, which is published by the American Psychological Association (APA). David Bunce, PhD, a psychologist at Goldsmith's College, University of London, Miia Kivipelto, PhD, MD, of the Aging Research Center at the Karolinska Institute in Stockholm and the Stockholm Gerontology Research Center, and Åke Wahlin, PhD, a psychologist at the University of Stockholm, conducted the study as part of a long-term multidisciplinary project that follows older people living in Stockholm's Kungsholmen parish.

Scientists already knew of a genetic predisposition for Alzheimer's disease, and that low levels of two B vitamins-- B12 and folate--were also linked to problems. However, few had examined nutrition and genotype together relative to cognition, to reflect what real people carry into old age – a mix of inborn traits and environmental factors such as nutrition, including undiagnosed vitamin B deficiencies.

The apolipoprotein E gene, which moves cholesterol in the body, has a version called the ?4 allele. Carried by perhaps 15 percent of the population, it is a risk factor for dementia. Current data collected over a six-year period suggests that nearly one out of four carriers with one copy of this allele and nearly half carrying two copies will develop Alzheimer's disease. Non-carriers also can get Alzheimer's.

Carriers of the ?4 allele have smaller hippocampi, brain areas associated with memory, so the researchers wanted to measure how an additional physiological shortfall such as low Vitamin B, affected this particular group -- given that reduced B12 and folate have been linked generally with diminished memory and increased risk for Alzheimer's. Perhaps 10 percent of adults aged 75 years and older have low B12 or folate.

Bunce, Kivipelto and Wahlin studied 167 healthy older people, averaging nearly 83 years old. First, they checked blood samples for vitamin levels and genotype. Some 82 participants had low B12 (28 with the ?4 allele; 54 without). The researchers then tested episodic memory, varying the test conditions to make them as sensitive as possible to underlying disorder.

Among carriers of the ?4 ApoE allele, people with normal B12 levels recalled a greater number of words. More time to encode (five as opposed to two seconds) also was associated with greater recall. More than doubling encoding time strengthened memory more for the ?4-low vitamin group than it did for other participants. A significant difference showed up in the experiment's most demanding condition, when participants had just two seconds to encode words. In that situation, the high-risk genotype plus low B12 levels was significantly associated with poorer memory.

The findings endorse a complex model of vulnerability in which genetic and non-genetic factors interact. According to the authors, "?4 ApoE carriers may derive relatively greater cognitive benefits from B12 and folate supplements. Supplement treatment is relatively inexpensive and may be required as part of preventive health regimes for older persons."

Article: "Utilization of cognitive support in episodic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older," David Bunce, PhD, Goldsmiths College, University of London; Miia Kivipelto, PhD, MD, Aging Research Center, Karolinska Institutet, Stockholm and Stockholm Gerontology Research Center; Åke Wahlin, PhD, University of Stockholm, Neuropsychology, Vol. 18, No. 2. (Full text of the article is available from the APA Public Affairs Office and at http://www.apa.org/releases/cognitivesupport_article.pdf )

Source: EurekAlert.org (this is a press release).



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get Energized with Malic Acid & Magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Safely Burn Away Body Fat Safely Burn Away Body Fat
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
How One Tiny Molecule Turned into One Huge Health Breakthrough How One Tiny Molecule Turned into One Huge Health Breakthrough
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map