ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Testosterone replacement therapy associated with improved urinary, sexual function

Cloves: Boost Your Immune System the Sweet and Spicy Way

8 Chia Seed Recipes

The Many Potential Health Benefits of Curcumin

 
Print Page
Email Article

Amantadine & L-carnitine treatment of Chronic Fatigue Syndrome (CFS)

  [ 56 votes ]   [ Discuss This Article ]
By Plioplys AV, Plioplys S • www.ProHealth.com • March 15, 1997


Carnitine is essential for mitochondrial energy production.
Disturbance in mitochondrial function may contribute to or
cause the fatigue seen in Chronic Fatigue Syndrome (CFS)
patients. Previous investigations have reported decreased
carnitine levels in CFS. Orally administered L-carnitine is
an effective medicine in treating the fatigue seen in a
number of chronic neurologic diseases. Amantadine is one of
the most effective medicines for treating the fatigue seen in
multiple sclerosis patients. Isolated reports suggest that it
may also be effective in treating CFS patients. Formal
investigations of the use of L-carnitine and amantadine for
treating CFS have not been previously reported. We treated 30
CFS patients in a crossover design comparing L-carnitine and
amantadine. Each medicine was given for 2 months, with a
2-week washout period between medicines. L-Carnitine or
amantadine was alternately assigned as fist medicine.

Amantadine was poorly tolerated by the CFS patients. Only 15
were able to complete 8 weeks of treatment, the others had to
stop taking the medicine due to side effects. In those
individuals who completed 8 weeks of treatment, there was no
statistically significant difference in any of the clinical
parameters that were followed. However, with L-carnitine we
found statistically significant clinical improvement in 12 of
the 18 studied parameters after 8 weeks of treatment. None of
the clinical parameters showed any deterioration. The
greatest improvement took place between 4 and 8 weeks of
L-carnitine treatment. Only 1 patient was unable to complete
8 weeks of treatment due to diarrhea. L-Carnitine is a safe
and very well tolerated medicine which improves the clinical
status of CFS patients. In this study we also analyzed
clinical and laboratory correlates of CFS symptomatology and
improvement parameters.




Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
The Super Antioxidant for Brain, Joint and Heart Health The Super Antioxidant for Brain, Joint and Heart Health
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map