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Immunoglobulin subclass levels in Chronic Fatigue Syndrome (CFS)

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By Bennett AL, Fagioli LR, Schur PH, Schacterle RS, Komaroff AL • www.ProHealth.com • November 6, 1996


The levels of immunoglobulin subclasses were determined for 46
patients meeting the original Centers for Disease Control case
definition of chronic fatigue syndrome and were compared to
values obtained for 50 age- and gender-matched healthy
volunteer blood donor controls. The levels of immunoglobulin
subclasses in these groups were further compared to a third
group of additional chronic fatigue syndrome cases from whom
samples had been obtained and frozen prospectively over a
period of 7 years. These data do not demonstrate significant
immunoglobulin subclass deficiencies in patients with chronic
fatigue syndrome.




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