Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

Greater intake of dietary omega-3 fatty acids associated with lower risk of diabetic retinopathy

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Researchers find herpes strain in the nervous system

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Nature Heals

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

 
Print Page
Email Article

Amitriptyline. A review of its pharmacological properties & therapeutic use in chronic pain states

  [ 26 votes ]   [ Discuss This Article ]
By Bryson HM, Wilde MI • www.ProHealth.com • June 10, 1996


Amitriptyline is a tricyclic antidepressant agent which also has
analgesic properties. Whether its analgesic effects are linked
to its mood-altering activity or attributable to a discrete
pharmacological action (or a combination of both) is unknown.
Clinical trials demonstrate that oral amitriptyline achieves
at least a good or moderate response in up to two-thirds of
patients with post-herpetic neuralgia and three-quarters of
patients with painful diabetic neuropathy, neurogenic pain
syndromes that are often unresponsive to narcotic analgesics.
Amitriptyline has also demonstrated efficacy in heterogeneous
groups of patients with chronic non-malignant pain. Other
possible areas of use for amitriptyline are in patients with
fibromyalgia or as an adjuvant for uncontrolled cancer pain,
although evidence for the latter application is limited.
Adverse events resulting from the antimuscarinic activity of
amitriptyline (primarily dry mouth and sedation) are commonly
reported, even at the low dosages used for the control of
pain. Low starting doses and careful dosage titration may
help to minimise these effects. Orthostatic hypotension and
tachycardia, sometimes associated with tricyclic
antidepressant agents, may also pose a problem in the elderly.
In summary, amitriptyline has a valuable place in the
treatment of chronic pain conditions that affect the elderly
provided that the drug is used judiciously to minimise
adverse effects. Importantly, amitriptyline remains the best
studied of the antidepressant agents in post-herpetic
neuralgia and diabetic neuropathy and is an important and
effective treatment option in these syndromes.




Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor® FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map