Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

Greater intake of dietary omega-3 fatty acids associated with lower risk of diabetic retinopathy

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Researchers find herpes strain in the nervous system

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Nature Heals

Best Herbs to Help With Insomnia

Meet the ProHealth Editors

Choline: Why You Should Eat Your Egg Yolks and Take Krill

 
Print Page
Email Article

FDA Approves Azulfidine EN-Tabs (Sulfasalazine) To Treat Rheumatoid Arthritis In Children

  [ 19 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 3, 2000


Children with juvenile rheumatoid arthritis involving five or more diseased joints, can turn to a newly approved drug for treatment. The U.S. Food and Drug Administration (FDA) has approved a new indication for Azulfidine EN-tabs® (sulfasalazine delayed release tablets) in patients who have responded inadequately to salicylates or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Azulfidine EN-tabs is the only formulation of sulfasalazine approved by the FDA for the treatment of both juvenile and adult RA. The enteric-coated formulation of Azulfidine EN-tabs was specifically designed to reduce the likelihood of nausea and stomach upset.

In a randomized, double-blind, placebo-controlled, clinical trial, sulfasalazine was evaluated in children with juvenile rheumatoid arthritis. This 24-week trial showed that sulfasalazine, compared to placebo, significantly reduced several clinical endpoints of joint disease including number and severity of swollen joints, number of active joints and overall joint severity score.

This clinical effectiveness of sulfasalazine was reinforced by significant reduction in disease activity scored by physicians, parents and patients.

"The FDA's approval of Azulfidine EN-tabs for juvenile rheumatoid arthritis gives clinicians in pediatric rheumatology an important new option to effectively manage this condition," said Arthur Weaver, M.D., director of clinical research at The Arthritis Center of Nebraska, and clinical professor at the University of Nebraska Medical Center.

In the treatment of adult RA, sulfasalazine, the active ingredient in Azulfidine EN-tabs, has been classified by the American College of Rheumatology as part of a group of compounds called disease-modifying anti-rheumatic drugs (DMARDs). While it has not been confirmed in children, DMARDs have the potential to reduce or prevent joint damage and preserve joint integrity and function. Rheumatoid Arthritis is a debilitating disease that affects 2.1 million Americans, of which 50,000 are children. The disease causes joint pain, stiffness and swelling in or around joints, as well as joint destruction.

Patients with intestinal or urinary obstructions, porphyria (pigment disorder) or hypersensitivity to sulfasalazine, sulfonamides or salicylates, should not use Azulfidine EN-tabs. The most common adverse reactions (incidence of 5 percent or greater) reported in RA clinical trials with sulfasalazine enteric-coated tablets were nausea, dyspepsia, rash, immunoglobulin suppression, headache, abdominal pain, vomiting and fever.



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Energy NADH™ 12.5mg Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Priming Your Immune System for Cold & Flu Season Priming Your Immune System for Cold & Flu Season
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map