ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Black Tea Is Great for Your Gut

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

 
Print Page
Email Article

FDA Approves Azulfidine EN-Tabs (Sulfasalazine) To Treat Rheumatoid Arthritis In Children

  [ 19 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 3, 2000


Children with juvenile rheumatoid arthritis involving five or more diseased joints, can turn to a newly approved drug for treatment. The U.S. Food and Drug Administration (FDA) has approved a new indication for Azulfidine EN-tabs® (sulfasalazine delayed release tablets) in patients who have responded inadequately to salicylates or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Azulfidine EN-tabs is the only formulation of sulfasalazine approved by the FDA for the treatment of both juvenile and adult RA. The enteric-coated formulation of Azulfidine EN-tabs was specifically designed to reduce the likelihood of nausea and stomach upset.

In a randomized, double-blind, placebo-controlled, clinical trial, sulfasalazine was evaluated in children with juvenile rheumatoid arthritis. This 24-week trial showed that sulfasalazine, compared to placebo, significantly reduced several clinical endpoints of joint disease including number and severity of swollen joints, number of active joints and overall joint severity score.

This clinical effectiveness of sulfasalazine was reinforced by significant reduction in disease activity scored by physicians, parents and patients.

"The FDA's approval of Azulfidine EN-tabs for juvenile rheumatoid arthritis gives clinicians in pediatric rheumatology an important new option to effectively manage this condition," said Arthur Weaver, M.D., director of clinical research at The Arthritis Center of Nebraska, and clinical professor at the University of Nebraska Medical Center.

In the treatment of adult RA, sulfasalazine, the active ingredient in Azulfidine EN-tabs, has been classified by the American College of Rheumatology as part of a group of compounds called disease-modifying anti-rheumatic drugs (DMARDs). While it has not been confirmed in children, DMARDs have the potential to reduce or prevent joint damage and preserve joint integrity and function. Rheumatoid Arthritis is a debilitating disease that affects 2.1 million Americans, of which 50,000 are children. The disease causes joint pain, stiffness and swelling in or around joints, as well as joint destruction.

Patients with intestinal or urinary obstructions, porphyria (pigment disorder) or hypersensitivity to sulfasalazine, sulfonamides or salicylates, should not use Azulfidine EN-tabs. The most common adverse reactions (incidence of 5 percent or greater) reported in RA clinical trials with sulfasalazine enteric-coated tablets were nausea, dyspepsia, rash, immunoglobulin suppression, headache, abdominal pain, vomiting and fever.



Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil FibroSleep™ Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Joint Aches May Have Met Their Match in Curcumin Joint Aches May Have Met Their Match in Curcumin
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Priming Your Immune System for Cold & Flu Season Priming Your Immune System for Cold & Flu Season

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map