ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

A Little Zinc Goes a Long Way

More evidence for calorie restriction’s longevity effect

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Iron (And More) For Lasting, Natural Energy

Get the Most From Your Green Tea

Affordable Care Act made cancer screening more accessible for millions, study finds

Metabolic syndrome increases the need for vitamin E

 
Print Page
Email Article

UGA Pharmacy Faculty Awarded Patent to Treat Neurodegenerative Disorders

  [ 170 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 29, 2005


Source: University of Georgia Two University of Georgia College of Pharmacy faculty have received a patent for the invention of novel analogs of choline that may be used to treat neurodegenerative disorders. Warren Beach, associate professor in the department of pharmaceutical and biomedical sciences, and Alvin Terry, professor in the department of clinical and administrative pharmacy, in collaboration with Jerry Buccafusco, director of the Alzheimer Research Center at the Medical College of Georgia, are developing novel compounds against such diseases as Alzheimer's, Parkinson's, Huntington's and related disorders. Compounds according to the present invention are effective to alleviate and/or reverse the effects of a neurodegenerative condition, prevent further deterioration and/or enhance cognition and memory in patients suffering from neurodegenerative disorders, especially Alzheimer's disease. "The new choline analogs are potentially useful in the treatment of any neurological condition where acetylcholine transmission neurons [cholinergic neurons] are affected," said Beach. These cholinergic neurons are involved in cognitive functions, such as learning and memory, and Alzheimer's disease is characterized by a loss of these neurons. Currently, Beach noted, the primary treatment of Alzheimer's is acetylcholine esterase inhibitors that inhibit the breakdown of acetylcholine in the brain, thus enhancing cholinergic transmission. Choline, the breakdown product of acetylcholine, has been shown to be protective against cell death. This protection arises through choline's stimulation of a receptor called Alpha 7 that is located on the acetylcholine neuron. "Choline has been evaluated as a treatment of Alzheimer's disease, however choline is not very potent and shows poor oral absorption. Several of our choline analogs are approximately 100,000 times more potent than choline in cell culture and should have better absorption characteristics and brain penetration than choline," said Beach.



Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida® Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map