ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Curcumin: The All In One Solution, Part 2

What Are the Benefits of Vitamin K2?

Vitamin D deficiency + high fat diet = metabolic syndrome

Use Burdock Oil to Promote Healthy Hair Growth

Why You Should Take Your Apple Cider Vinegar at Night

AMA journal associates iron deficiency with hearing loss

Lutein linked to preservation of crystallized intelligence

People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, resea...

Zinc eaten at levels found in biofortified crops reduces 'wear and tear' on DNA

A handful of nuts a day cuts the risk of a wide range of diseases

 
Print Page
Email Article

Riedel's thyroiditis: treatment with tamoxifen

  [ 67 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 20, 1996


BACKGROUND: Riedel's thyroiditis is an often disabling disease with
clinical and histologic similarity to several other fibrous
inflammatory disorders. Surgical treatment alone is often
unsatisfactory in permanently alleviating airway compression,
dysphagia, neck immobility, pain, or chronic fatigue syndrome.
Investigation of drugs shown to be of benefit in the
treatment of related fibrous disorders in which hormonal
factors or inflammatory deregulation appear to be important
is indicated. Tamoxifen has not been previously used in the
treatment of Riedel's thyroiditis.
METHODS: Four patients
with clinical and histologic diagnoses of Riedel's
thyroiditis were evaluated before and after treatment with
tamoxifen. Each had progressive symptomatic disease of 3 to
16 years' duration despite one or more surgical procedures
and steroid therapy. Subjective improvement was noted in all
cases, and objective changes were confirmed by periodic
physical and computed tomographic examinations.
RESULTS:
Patients have been monitored for 1 to 4 years with subjective
improvement in 100% and objective disease regression ranging
from 50% to 100% in all patients. One patient had complete
regression within 6 months, and another had more than 50%
regression within 3 months. All have returned to predisease
activity levels. There were no significant side effects of
the therapy.
CONCLUSIONS: Tamoxifen has proved to be the most
effective drug therapy available for managing Riedel's
thyroiditis. Our studies suggest that this is unrelated to
antiestrogen activity. Tamoxifen's effectiveness may be caused
by a mechanism by which it stimulates the release of
transforming growth factor-beta, which may inhibit the
fibroblastic proliferation characteristic of Riedel's
thyroiditis.

Few J, Thompson NW, Angelos P, Simeone D, Giordano T, Reeve T




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg FibroSleep™ Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map