ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

Scientifically-designed fasting diet lowers risks for major diseases

How One Tiny Molecule Turned into One Huge Health Breakthrough

Acupuncture boosts effectiveness of standard medical care for chronic pain, depression

Research on Astaxanthin Demonstrates Significant Whole Body Benefits

Humans have three times more brown body fat

Nutrients Boost Stem Cell Function

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

Dietary prebiotics improve sleep, buffer impacts of stress, says study

Print Page
Email Article

Modulation of pressure pain thresholds during & following isometric contraction in patients with fibromyalgia (FM) & in healthy controls

  [ 12 votes ]   [ Discuss This Article ] • March 15, 1996

This study aimed at evaluating the influence of submaximal
isometric contraction on pressure pain thresholds (PPTs) in 14
fibromyalgia (FM) patients and 14 healthy volunteers, before
and after skin hypoesthesia. PPTs were determined with
pressure algometry over m. quadriceps femoris before, during
and following an isometric contraction. Maximum voluntary
contraction (MVC) was assessed using a computerized
dynamometer. A contraction of 22% MVC on average was held
until exhaustion (max. 5 min) and PPTs were assessed every 30
sec. A local anesthetic cream and a control cream were
applied following a double-blind design and PPTs were
reassessed. In healthy volunteers PPTs increased during
contraction (P < 0.001), then decreased after the end of
contraction (P < 0.001) but remained above precontraction
values during the 5 min of post-contraction assessments (P <
0.001). In FM patients PPTs decreased in the middle of the
contraction period (P < 0.05) and remained below
precontraction levels during the rest of the contraction
period (P < 0.05) and during the 5 min of post-contraction
assessment (immediately post-contraction NS; 2.5 min
post-contraction P < 0.01; 5 min post-contraction P < 0.05).
The normalized PPTs were significantly lower in patients than
in controls during contraction (start P < 0.01; middle P <
0.001; end P < 0.001) and at all times during post-contraction
assessments (P < 0.001). Anesthetic cream raised PPTs at rest
in controls (P < 0.01) but not in FM patients, and did not
influence contraction or post-contraction PPTs in either
group. Therefore, the increased pressure pain sensibility in
FM patients is more pronounced deep to the skin. The observed
decrease of PPTs during isometric contraction in FM patients
could be due to sensitization of mechanonociceptors caused by
muscle ischemia and/or dysfunction in pain modulation during
muscle contraction.

Kosek E, Ekholm J, Hansson P

Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

NAD+ Ignite with Niagen

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
The Curcumin Revolution: 'Golden' Ticket to Better Health The Curcumin Revolution: 'Golden' Ticket to Better Health

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map