ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

On-and-off fasting helps fight obesity, study finds

16 Tips from 16 Years Sick

Fibromyalgia Fare Fit for All Seasons

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Higher vitamin D levels associated with less severe disease in NAFLD patients

Can Pomegranates Slow Aging?

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

How zinc helps fight esophageal cancer

What Benefits Can You Get From High-Quality Whey Protein?

 
Print Page
Email Article

A case-control study to assess possible triggers & cofactors in Chronic Fatigue Syndrome (CFS)

  [ 89 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 20, 1996


PURPOSE: To assess possible triggers and cofactors for chronic
fatigue syndrome (CFS) and to compare levels of selected
cytokines between cases and an appropriately matched control
group.

PATIENTS AND METHODS: We conducted a case-control study
of 47 cases of CFS obtained through a regional CFS research
program maintained at a tertiary care medical center. One
age-, gender-, and neighborhood-matched control was identified
for each case through systematic community telephone sampling.
Standardized questionnaires were administered to cases and
controls. Sera were assayed for transforming growth
factor-beta (TGF-beta), interleukin-1 beta, interleukin-6,
tumor necrosis factor-alpha, and antibody to Borrelia
burgdorferi and Babesia microti.

RESULTS: Cases were more
likely to have exercised regularly before illness onset than
controls (67% versus 40%; matched odds ratio (MOR) = 3.4; 95%
CI = 1.2 to 11.8; P = 0.02). Female cases were more likely to
be nulliparous prior to onset of CFS than controls (51% versus
31%; MOR = 8.0; 95% CI = 1.03 to 170; P = 0.05). History of
other major factors, including silicone-gel breast implants
(one female case and one female control), pre-morbid history
of depression (15% of cases, 11% of controls) and history of
allergies (66% of cases, 51% of controls) were similar for
cases and controls. However, cases were more likely to have a
diagnosis of depression subsequent to their diagnosis of CFS
compared to a similar time frame for controls (MOR =
undefined; 95% CI lower bound = 2.5; P < 0.001). Positive
antibody titers to B burgdorferi (one case and one control)
and B microti (zero cases and two controls) were also similar.

CONCLUSIONS: Further investigation into the role of prior
routine exercise as a cofactor for CFS is warranted. This
study supports the concurrence of CFS and depression, although
pre-morbid history of depression was similar for both groups.

MacDonald KL, Osterholm MT, LeDell KH, White KE, Schenck CH, Chao
CC, Persing DH, Johnson RC, Barker JM, Peterson PK




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor® Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Joint Aches May Have Met Their Match in Curcumin Joint Aches May Have Met Their Match in Curcumin
Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
How One Tiny Molecule Turned into One Huge Health Breakthrough How One Tiny Molecule Turned into One Huge Health Breakthrough
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map