ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

Testosterone replacement therapy associated with improved urinary, sexual function

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

The Many Potential Health Benefits of Curcumin

8 Chia Seed Recipes

 
Print Page
Email Article

Investigation by polymerase chain reaction of enteroviral infection in patients with Chronic Fatigue Syndrome (CFS)

  [ 36 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 15, 1996


1. Chronic fatigue syndrome is characterized by muscle fatigue and
pain at rest, symptoms which are usually exacerbated with
exercise. Although various studies have shown minor,
non-specific morphological and biochemical changes in muscle
of patients with chronic fatigue syndrome, no consistent
defect has been identified. Some have suggested that an
enteroviral infection in muscle may cause the chronic muscle
fatigue seen in patients with chronic fatigue syndrome, with
acute infection directly and irreversibly impairing
mitochondrial function, and persistent infection depressing
muscle protein synthesis and metabolism.

2. To clarify the
involvement of enterovirus infection in chronic fatigue
syndrome, muscle biopsies from a group of patients with
chronic fatigue syndrome were examined for the presence of
enteroviral RNA by reverse transcriptase-polymerase chain
reaction techniques in relation to functional studies of
muscle mitochondria and the muscle RNA/DNA ratio.

3. Fifty-eight percent of patients reported an uncharacterized
'viral infection' before the onset of their illness, but none
of the muscle samples from 34 patients contained detectable
amounts of enteroviral RNA. Muscle tissue had a general
reduction in the RNA/DNA ratio and mitochondrial enzyme
activities with no specific abnormality in the activity of
enzymes encoded partially on the mitochondrial genome
(cytochrome-c oxidase) or nuclear genome (citrate synthase,
succinate reductase).

4. These data provide no evidence of an
enteroviral infection in muscle of patients with chronic
fatigue syndrome, although this does not exclude a role of
enterovirus in initiating the disease process. The general
reduction in RNA/DNA ratio and mitochondrial enzyme activities
is consistent with a general reduction in habitual activity.

McArdle A, McArdle F, Jackson MJ, Page SF, Fahal I, Edwards RH




Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor® Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map