ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

A Breathalyzer for Disease?

Why You Should Be Eating More Porcini Mushrooms

Tryptophan's Possible Effects for Your Health

How Bacopa Can Help Improve Your Cognitive Function

Black Tea Is Great for Your Gut

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Mint: Learn More About This Refreshing and Invigorating Herb

 
Print Page
Email Article

Preliminary determination of a molecular basis of Chronic Fatigue Syndrome (CFS)

  [ 17 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 12, 1996


Chronic fatigue syndrome (CFS/ME) is a debilitating fatigue
illness that has an unknown etiology. We studied 20 chronic
fatigue syndrome (CFS) patients, who complied with the Oxford
and American CDC definitions, and 45 non-CFS subjects.
Participants completed questionnaires, were clinically
examined, and had first morning urine specimens collected,
which were screened by gas chromatography-mass spectrometry
for changes in metabolite excretion. Multivariate analysis of
the urinary metabolite profiles differed significantly in the
CFS patients compared to the non-CFS patients (P < 0.004).
The CFS patients had increases in
aminohydroxy-N-methylpyrrolidine (P < 0.00003, referred to as
chronic fatigue symptom urinary marker 1, or CFSUM1), tyrosine
(P < 0.02), beta-alanine (P < 0.02), aconitic acid (P <
0.05), and succinic acid (P < 0.05) and reductions in an
unidentified urinary metabolite, CFSUM2 (P < 0.0007), alanine
(P < 0.005), and glutamic acid (P < 0.02). CFSUM1,
beta-alanine, and CFSUM2 were found by discriminant function
analysis to be the first, second, and third most important
metabolites, respectively for discriminating between CFS and
non-CFS subjects. The abundances of CFSUM1 and beta-alanine
were positively correlated with symptom incidence (P < 0.01
and P < 0.001, respectively), symptom severity, core CFS
symptoms, and SCL-90-R somatization (P < 0.00001),
suggesting a molecular basis for CFS.

McGregor NR, Dunstan RH, Zerbes M AU - Butt HL, Roberts TK,
Klineberg IJ




Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil FibroSleep™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map