ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Scientifically-designed fasting diet lowers risks for major diseases

More evidence for calorie restriction’s longevity effect

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

A Little Zinc Goes a Long Way

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Get the Most From Your Green Tea

Iron (And More) For Lasting, Natural Energy

Metabolic syndrome increases the need for vitamin E

Supplement combo improves bone density, mood, in postmenopausal women

 
Print Page
Email Article

Randomized, double blind, controlled placebo-phase in trial of low dose phenelzine in the Chronic Fatigue Syndrome (CFS)

  [ 55 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 15, 1996


Because of the striking similarity of the clinical manifestations
produced by use of the drug reserpine and seen in patients
with the chronic fatigue syndrome (CFS), we theorized that
CFS was a disorder of reduced central sympathetic drive.
Because of the pharmacology of control of this central
sympathetic system, we further postulated that CFS symptoms
would respond quickly to low dose treatment with a monamine
oxidase inhibitor. To test these hypotheses, we designed a
randomized, double blind placebo controlled study using
phenelzine. No patient in the trial had a diagnosis of
lifetime or current psychiatric disorder and none had
depressed mood in the range of clinically depressed patients
on a paper and pencil test of depression. Patients in the
placebo group received placebo for 6 weeks while those in the
drug treatment group were treated in three 2-week
segments-placebo, 15 mg phenelzine every other day, and then
15 mg daily. This treatment regimen produced a significant
pattern of improvement compared to worsening in 20 self
report vehicles of CFS symptoms, illness severity, mood or
functional status. Thus the data support our hypothesis of
reduced sympathetic drive, although an alternative hypothesis
of pain alleviation is also possible. The study design also
allowed us to evaluate patients for a placebo effect: no
evidence for this was found, suggesting that CFS is not an
illness due to patients' being overly suggestible.

Natelson BH, Cheu J, Pareja J, Ellis SP, Policastro T, Findley TW




Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Energy NADH™ 12.5mg FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Help for Soreness and Swelling: What Do Silkworms Have to Do With It? Help for Soreness and Swelling: What Do Silkworms Have to Do With It?
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map