ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Natural Remedies for the Prevention of Dry Eyes

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

8 Chia Seed Recipes

Cinnamon Health Benefits Proven

 
Print Page
Email Article

Fewer Calories May Slow Alzheimer's

  [ 109 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 20, 2004


Source: University of Southern California

A restrictive diet in mice reduces the build-up of a substance linked to memory loss. But can the findngs be applied to humans? Restricting the diets of mice reduces the build-up of plaques in the brain that are linked to Alzheimer's disease, according to a USC study. With obese people generally considered to be at a higher risk for developing Alzheimer's, the research raises questions about whether the findings are potentially applicable to humans. "This is the first indication that modest changes in the normal diet can slow some aspects of Alzheimer's disease," said Caleb Finch, co-author of the study published in the online version of the journal Neurobiology of Aging. "But that is far and away yet to be proven for humans. It's a big jump to say that what's true for a mouse in a cage is relevant to people living in our complex world," Finch said.

In the study, conducted with collaborators at the University of South Florida in Tampa, researchers used mice whose DNA had been altered with human genes from two families with early onset hereditary Alzheimer's. The mice were then split into two groups as young adults: one that could eat all it desired ("ad libitum") and the other that had its food intake reduced by 40 percent over a four-week period (diet- restricted). The researchers were looking specifically at the formation of plaques caused by a build-up of the fiber-like substance called beta-amyloid. Made up of proteins and polysaccharides, amyloid plaques are deposited in the brain during Alzheimer's disease. Specifically, plaques accumulate in the hippocampus and frontal cortex of Alzheimer's sufferers - areas responsible for memory. In the diet-restricted mice, both the amount and size of plaque was about 50 percent less than in mice that ate as much as they wanted. "The power of this study is that two different sets of [human] family mutations were equally sensitive to the effect of diet and slowing the Alzheimer's-like change," said Finch, holder of the ARCO-William F. Kieschnick Chair in the Neurobiology of Aging at USC.

The next goal is to find out why diet restriction has such profound and rapid effects, Finch said. "We are going to look into the details of metabolism to try and isolate which of the consequences of diet restriction is at work," Finch said. "Is it the blood glucose? Is it the lowered insulin? Those are two targets." The other USC researchers on this study were Nilay V. Patel, a former USC postdoc who is now a staff scientist at City of Hope Medical Center, and Todd E. Morgan, a research assistant professor in the Andrus Gerontology Center at USC. The researchers at the University of Southern Florida are Marcia Gordon, Karen E. Connor, Robert A. Good, Robert W. Engelman, Jerimiah Mason and David G. Morgan.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Ultra EPA  - Fish Oil


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map