ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Lilac Oil: More Than Just for Fragrance

Eat More Yogurt and Avoid Osteoporosis

What Is Bilberry Good For?

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Higher omega 3 levels linked to improved brain blood flow

Curcumin, resveratrol, ursolic acid show promise against prostate cancer

Olive oil compound could help protect against brain cancer

 
Print Page
Email Article

Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of Chronic Fatigue Syndrome (CFS)

  [ 72 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 10, 1996


BACKGROUND: There is no established treatment for chronic fatigue
syndrome (CFS), an illness characterized by disabling fatigue
exacerbated by physical activity. A variety of immunologic
abnormalities have been reported, including a high incidence
of atopy and hypoergy or anergy.

OBJECTIVE: Because of
anecdotal reports and uncontrolled trials showing
antihistamine efficacy in CFS, we evaluated the clinical
efficacy of the antihistamine terfenadine (60 mg twice daily)
in a placebo-controlled study.

METHODS: Thirty patients with
CFS were enrolled in a 2-month, double-blind,
placebo-controlled trial of terfenadine. Participants
underwent a battery of both immediate- and delayed-type
hypersensitivity skin tests and completed a self-assessment
questionnaire used to measure severity of symptoms, physical
and social functioning, health perceptions, and mental health
before each of six biweekly visits.

RESULTS: Twenty-eight
patients completed the trial. History of atopy and positive
immediate skin test results were prevalent, 73% and 53%,
respectively. No evidence for hypoergy or anergy after
delayed-type hypersensitivity skin testing was found. No
therapeutic benefit from terfenadine could be detected in
terms of symptom amelioration, improved physical or social
functioning, health perceptions, or mental health. A high
incidence of atopy in patients with CFS was confirmed.

CONCLUSION: Although this trial involved a small number of
patients, the results suggest that terfenadine is unlikely to
be of clinical benefit in treating CFS symptoms.

Steinberg P, McNutt BE, Marshall P, Schenck C, Lurie N, Pheley A,
Peterson PK




Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Ultra EPA  - Fish Oil FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
"It's Not Easy Being Green" - But It Is Healthy

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map