ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

Could Coconut Oil Help Reduce Antibiotics?

 
Print Page
Email Article

Quercetin and Vitamin C May Help Protect the Brain

  [ 249 votes ]   [ Discuss This Article ]
www.ProHealth.com • February 14, 2005


Source: Roman Bystrianyk, "Quercetin and Vitamin C May Protect the Brain", Health Sentinel, February 7, 2005

According to the Alzheimer’s Association, an estimated 4.5 million Americans have Alzheimer’s disease, with the number of Americans with Alzheimer’s more than doubling since 1980. Also, according to the National Institutes of Health, Parkinson's disease affects between 1 and 1.5 million individuals in the United States, with some 20,000 new cases diagnosed each year. This means that an estimated 200 people in every 100,000 suffer from Parkinson's disease.

A study published in the December issue of the Journal of Agricultural and Food Chemistry looks at how oxidative stress plays a role in these conditions and the shielding effect of quercetin and vitamin C in protecting the brain from this damage. There is evidence that oxidative stress plays a role in Alzheimer and Parkinson's diseases. It appears that oxidative stress causes cumulative damage and could be responsible for the late life onset and slow progression of these illnesses. Brains cells are rich in polyunsaturated fats and because of lower levels of antioxidant chemicals, such as glutathione, in the brain; these cells are especially vulnerable to free radical attack. Vitamin C is a water-soluble antioxidant that has been shown to help decrease the risk of Alzheimer’s. Quercetin is a flavonoid that has antioxidant and free radical scavenging properties.

The authors of the study exposed cell cultures to oxidative stress in the form of hydrogen peroxide (H202), with some cells pretreated with different amounts of quercetin or vitamin C. Those cells that were pretreated with quercetin or vitamin C were significantly more protected than those that were not pretreated. The protection was dose dependent with quercetin having a higher protective effect than vitamin C. There was a 4-fold increase in cell viability with those neuronal cells treated with quercetin or vitamin C at the highest dose. The authors state that, “our data also showed that quercetin has more cell protective effect than vitamin C. These results suggest that quercetin and vitamin C with excellent antioxidant activities could protect the neuronal cell membrane against H202-induced neurotoxicity, although the protective effect of vitamin C was not strong compared to that of quercetin.”

Because of the blood-brain barrier (BBB), many chemicals cannot pass into the brain, thus limiting drug delivery to the brain. It has been shown that quercetin can flux into the brain. The authors conclude that, “it is possible that quercetin with beneficial antioxidant and biological functions is able to penetrate the BBB and can protect the H202-induced cytotoxicity.”

Study reference: Journal of Agricultural and Food Chemistry, December 15, 2004



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Ultra ATP+, Double Strength Ultra EPA  - Fish Oil


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage
Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map