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The effect of social adversity on the fatigue syndrome, psychiatric disorders & physical recovery, following glandular fever

  [ 53 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 2, 1994


Two hundred and fifty patients attending primary care with glandular
fever or an upper respiratory tract infection were studied
prospectively up to 6 months after onset. Of these patients
228 were interviewed with the Life Events and Difficulties
Schedule and the Schedule for Affective Disorders and
Schzophrenia, giving Research Diagnostic Criteria for
psychiatric disorders. The experience of severe social
adversity (provoking agents) had a significant association
with psychiatric disorder at 2 months (odds ratio = 5.3) and 6
months (odds ratio = 5.8) after onset of infection. This
association was especially significant for depressive illness
(odds ratio = 9.1 at 2 months and 11.9 at 6 months). In
contrast, social adversity had little association with the
development of the post-infectious fatigue syndrome, or
delayed physical recovery. Social adversity may be an
important maintaining factor for psychiatric disorders,
especially depressive illness, following acute infections.

Bruce-Jones WD, White PD, Thomas JM, Clare AW




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