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Effects of magnesium, high energy phosphates, piracetam & thiamin on erythrocyte transketolase

  [ 27 votes ]   [ Discuss This Article ]
www.ProHealth.com • March 2, 1994


Erythrocyte transketolase activity coefficient (ETK-AC) and affinity
for coenzyme (Km TPP) were assessed in 50 patients with
transketolase abnormalities such as fibromyalgia or senile
dementia of Alzheimer's type, before and after magnesium (Mg),
thiamin+pyridoxine (B1,B6), high energy phosphates (HEP)
(phosphocreatinine of adenosine triphosphate), and piracetam.
Compared to 12 untreated patients, ETK-AC was significantly
decreased with B1,B6 (P < 0.05, n = 10); Km-TPP was
significantly decreased with HEP (P < 0.05, n = 20) and
piracetam (P < 0.01, n = 5). In nine other patients treated
with HEP + B1,B6 + magnesium, ETK-AC and Km TPP were both
significantly decreased.

Eisinger J, Bagneres D, Arroyo P, Plantamura A, Ayavou T




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