ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Discover Why Ashwagandha Can Be Used for Stress and Anxiety

How Can You Benefit From Vitamin B12?

Calorie restriction promotes longevity through effects on mitochondrial network

Lower magnesium levels linked with increased mortality risk during up to 40 years of follow-up

Higher resveratrol dose linked to lower glucose levels in type 2 diabetics

What Is Bitter Orange?

Black Tea Is Great for Your Gut

Drug can dramatically reduce weight of people with obesity

Tryptophan's Possible Effects for Your Health

New Finding: Broccoli Helps Heal Leaky Gut

 
Print Page
Email Article

Eicosanoids & essential fatty acid modulation in chronic disease & the Chronic Fatigue Syndrome (CFS)

  [ 96 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 3, 1994


Abnormalities of Essential Fatty Acid (EFA) incorporation into
phospholipid are found in chronic diseases. More recently
changes in circulating EFA metabolites (EFAM) together with
EFAM hypo-responsiveness of immune cells and EFAM production
from cells have been found associated with disease. We
hypothesize that changes in ratio of EFAMs are the normal
physiological responses to stressors, but when stressors are
excessive or prolonged, EFAM systems may become unpredictably
hypo-responsive owing to factors such as receptor down
regulation and substrate depletion. In time, many homeostatic
system become deranged and held in that state by minor
stressors. Literature review of chronic fatigue syndrome (CFS)
shows hyper and hypo-responsiveness in immune function,
several Hypothalamo-Pituitary (HP) axes and sympathetic
nervous system, all relatable to dysfunctional changes in EFA
metabolism. For the first time, we explain chronic immune
system activation and hypo-responsive immune function in CFS;
through EFAMs. Dietary EFA modulation (DEFA) can alter ratios
of both membrane EFAs and produced EFAMs, and if maintained
can restore hypo-responsive function. We discuss dietary
strategies and relevance in CFS, and a case series of CFS
patients applying DEFA with other titrated published
managements which saw 90% gaining improvement within 3 months
and more than 2/3 fit for full time duties. This hypothesis
and DEFA may have relevance in other chronic conditions.

Gray JB, Martinovic AM




Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Fighting Fatigue with Ground-breaking French Oak Wood Extract Fighting Fatigue with Ground-breaking French Oak Wood Extract
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map