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Cold-induced vasospasm in patients with fibromyalgia (FM) & chronic low back pain in comparison to healthy subjects

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www.ProHealth.com • September 2, 1994


Using capillary videomicroscopy of the nail fold, the
frequency of cold-induced vasospasm and capillary hemodynamic
parameters were studied after application of cold in 50
patients with primary fibromyalgia, 50 patients with chronic
low back pain, and 50 healthy controls. Cold-induced vasospasm
was detected in 38% of the patients with fibromyalgia. In this
group it was significantly more frequent than in the patients
with chronic low back pain (20%, p < 0.05) and healthy
subjects (8%, p < 0.001). In the fibromyalgia group, the
magnitude of vasospasm as measured by the capillary blood flow
deceleration after cold application correlated negatively with
the pain intensity as measured by pain score (r = -0.3839, p <
0.01). No differences in clinical appearance were found
between patients with and without cold-induced vasospasm in
both the fibromyalgia and low back pain group.

Lapossy E, Gasser P, Hrycaj P, Dubler B, Samborski W, Muller W




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