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Fatigue secondary to chronic illness: postpolio syndrome [PPS], Chronic Fatigue Syndrome (CFS), & multiple sclerosis

  [ 22 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 2, 1994


Estimates of the percentage of patients with postpolio
syndrome, chronic fatigue syndrome, and multiple sclerosis who
experience fatigue range from approximately 75% to 100%. In
this study we describe the severity of fatigue and its impact
on subjects with these three diagnoses. The Fatigue Severity
Scale, the Human Activity Profile, and the Nottingham Health
Profile were used to measure fatigue, activity, and health
status respectively of each diagnostic group as well as a
control group. Using a Kruskal-Wallis one-way analysis of
variance followed by a Bonferroni-adjusted Mann Whitney U test
all diagnostic groups reported significantly higher levels (p
= .0000 to p = .002) of fatigue and lower perceived health
status than the control group. Subjects with chronic fatigue
and multiple sclerosis also had significantly reduced activity
levels (p = .002 to p = .01) compared with the control group.
Further attention should be directed toward understanding the
relationship between fatigue and ability to engage in
activities as well as strategies for remediation and/or
compensation of the fatigue.

Packer TL, Sauriol A, Brouwer B




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