ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

A Little Zinc Goes a Long Way

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

Vitamin D deficiency increases risk of chronic headache

Wearable biosensors can flag illness, Lyme disease, risk for diabetes; low airplane oxygen

VIDEO: The Best Brain Foods That Help Increase Your Memory!

More evidence for calorie restriction’s longevity effect

Iron (And More) For Lasting, Natural Energy

Affordable Care Act made cancer screening more accessible for millions, study finds

Metabolic syndrome increases the need for vitamin E

 
Print Page
Email Article

Dysregulated expression of tumor necrosis factor in Chronic Fatigue Syndrome (CFS): interrelations with cellular sources & patterns of soluble immune mediator expression

  [ 31 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 3, 1994


Among a group of 70 individuals who met the criteria
established by the Centers for Disease Control and Prevention
(Atlanta) for chronic fatigue syndrome (CFS), 12%-28% had
serum levels exceeding 95% of control values for tumor
necrosis factor (TNF) alpha, TNF-beta, interleukin (IL) 1
alpha, IL-2, soluble IL-2 receptor (sIL-2R), or neopterin;
overall, 60% of patients had elevated levels of one or more of
the nine soluble immune mediators tested. Nevertheless, only
the distributions for circulating levels of TNF-alpha and
TNF-beta differed significantly in the two populations. In
patients with CFS--but not in controls--serum levels of
TNF-alpha, IL-1 alpha, IL-4, and sIL-2R correlated
significantly with one another and (in the 10 cases analyzed)
with relative amounts (as compared to beta-globin or
beta-actin) of the only mRNAs detectable by reverse
transcriptase-coupled polymerase chain reaction in
peripheral-blood mononuclear cells: TNF-beta, unspliced and
spliced; IL-1 beta, lymphocyte fraction; and IL-6 (in order of
appearance). These findings point to polycellular activation
and may be relevant to the etiology and nosology of CFS.

Patarca R, Klimas NG, Lugtendorf S, Antoni M, Fletcher MA




Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Mitochondria Ignite™ with NT Factor® Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
Break Free From Fibromyalgia Break Free From Fibromyalgia
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map