ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

B Vitamins May Protect Against Damaging Effects of Air Pollution, and Improve Cognition and Psychiat...

Relief for IBS, Colitis, Crohn’s And More

Can Magnesium Relieve Your Tinnitus?

Restless Leg Syndrome (RLS) - are you running a marathon each night?

Resveratrol Proven to Slow Brain Aging

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Fruits and vegetables' latest superpower? Lowering blood pressure

Neroli Oil: The Pleasantly Fragrant Citrus Oil

Restoring NAD+ could reduce DNA damage accumulation

Whole-body vibration may be as effective as regular exercise

 
Print Page
Email Article

Dysregulated expression of tumor necrosis factor in Chronic Fatigue Syndrome (CFS): interrelations with cellular sources & patterns of soluble immune mediator expression

  [ 31 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 3, 1994


Among a group of 70 individuals who met the criteria
established by the Centers for Disease Control and Prevention
(Atlanta) for chronic fatigue syndrome (CFS), 12%-28% had
serum levels exceeding 95% of control values for tumor
necrosis factor (TNF) alpha, TNF-beta, interleukin (IL) 1
alpha, IL-2, soluble IL-2 receptor (sIL-2R), or neopterin;
overall, 60% of patients had elevated levels of one or more of
the nine soluble immune mediators tested. Nevertheless, only
the distributions for circulating levels of TNF-alpha and
TNF-beta differed significantly in the two populations. In
patients with CFS--but not in controls--serum levels of
TNF-alpha, IL-1 alpha, IL-4, and sIL-2R correlated
significantly with one another and (in the 10 cases analyzed)
with relative amounts (as compared to beta-globin or
beta-actin) of the only mRNAs detectable by reverse
transcriptase-coupled polymerase chain reaction in
peripheral-blood mononuclear cells: TNF-beta, unspliced and
spliced; IL-1 beta, lymphocyte fraction; and IL-6 (in order of
appearance). These findings point to polycellular activation
and may be relevant to the etiology and nosology of CFS.

Patarca R, Klimas NG, Lugtendorf S, Antoni M, Fletcher MA




Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Ultra EPA  - Fish Oil Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
The Super Antioxidant for Brain, Joint and Heart Health The Super Antioxidant for Brain, Joint and Heart Health
Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Help for Soreness and Swelling: What Do Silkworms Have to Do With It? Help for Soreness and Swelling: What Do Silkworms Have to Do With It?
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map