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Single fibre EMG studies in Chronic Fatigue Syndrome (CFS): a reappraisal

  [ 30 votes ]   [ Discuss This Article ]
www.ProHealth.com • March 2, 1994


Single fibre EMG studies were carried out on the right extensor
digitorum communis muscle in 30 subjects with chronic fatigue
syndrome and in 30 age and sex matched controls. Abnormal
jitter was seen in five patients with chronic fatigue
syndrome.

Slight but significant differences between the mean
consecutive differences in the remainder of the chronic
fatigue subjects and the control subjects were recorded.
Overall the differences were so minor that it seems unlikely
that a disturbance of neuromuscular function as reflected by
jitter measurement has a pathogenetic role. It is suggested
that the increased jitter seen may be explained by the effects
of the variability of motor unit firing rates on the myogenic
component of the jitter.

Roberts L, Byrne E




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