ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Coconut Oil Healthy? (The American Heart Association Doesn’t Think So)

American Heart Association Renders Itself Obsolete With 1960s Dietary Advice on Coconut Oil

How Fish Oil Benefits Heart Disease Patients with Depression

Ginger Fights Obesity

Health Benefits of Artichokes

Putting the Spotlight on Coriander Seed Oil

Migraines? Powdered Ginger May Help

Are Americans Really Getting Too Much Vitamin D? A Critical Look at Recent Media Warnings

Eating more vegetable protein may protect against early menopause

Vitamin C and antibiotics: A new one-two 'punch' for knocking-out cancer stem cells

 
Print Page
Email Article

University of Kentucky Researcher Identifies Key to Macular Degeneration Progression

  [ 237 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 30, 2006


Source: University of Kentucky Dr. Jayakrishna Ambati UK HealthCare physician and Associate Professor and Vice Chair of the Department of Ophthalmology and Visual Sciences, announced a discovery by his research team that will impact how physicians and patients approach treatment for macular degeneration. Age-related macular degeneration (AMD) is the leading cause of permanent vision loss among the elderly in many industrialized countries, including the United States. Approximately 15 million people in the U.S. have the early "dry" form of macular degeneration. Of those patients, about ten to 20 percent go on to develop the late-stage or "wet" form of the disease. The earliest clinical indicator of macular degeneration is the presence of drusen, or extracellular deposits that accumulate beneath the retinal pigmented epithelium. Although science has known for some time that the presence of drusen is a risk factor for the development of late-stage AMD, it has been unclear whether or how drusen can provoke the development of the wet form of AMD. Drusen in patients with AMD contain components known as complement C3 and C5. Ambati's lab has identified that bioactive fragments of these components, known as C3a and C5a, are present in patients whose AMD progresses beyond the early dry stage and into the later wet stage. Ambati's research concludes that the presence of the C3a and C5a components in drusen are not only markers of AMD that will develop into the late-stage form of the disease, but that they are in fact causal. The presence of these components stimulates the progression of AMD. In the future, patients with early-stage AMD may be screened to determine if these effectors exist in their drusen. If they are present, then these patients could be considered at "high risk" for progression to advanced AMD. The next step for Ambati's research is to develop a substance that can block the effectors, halting the progression of AMD from the dry to wet stages. His lab is already testing such substances that could potentially be used in patients with "high-risk" drusen. Ambati's research, which was supported by the National Eye Institute, is published in the current issue of Proceedings of the National Academy of Sciences. More information is available at http://www.pnas.org/papbyrecent.shtml.



Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida® Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Breaking Through the Mental Fog Breaking Through the Mental Fog
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map