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Fibromyalgia (FM) & the facts. Sense or nonsense

  [ 41 votes ]   [ Discuss This Article ] • February 3, 1993

A recent flurry of important studies has provided critical new
information that is relevant to the contemporary understanding
of the fibromyalgia syndrome. The concept that these patients
represent solely a form of masked depression or a distinctive
syndrome of somatization is not supported by the current
facts. Rather it would appear that a characteristic peripheral
nociceptive component is modulated by an interplay of complex
central factors. A disruption of the neuroendocrine axis
controlling growth hormone production may be the link between
disturbed sleep and muscle pain, as growth hormone is produced
predominantly during stage four sleep. A paradigm to link some
of these newer findings is presented.

Bennett RM

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